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Management Flashcards

1
Q

What is the gold standard investigation for bacterial STIs?

A

Culture from urethral/rectal smear

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2
Q

What is the gold standard investigation for TB?

A

3 Sputum Samples
Ziehl-Neelson Stain
Lowenstein-Jensen Medium

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3
Q

What is the gold standard diagnostic test for Acromegaly?

A

OGTT

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4
Q

What is the gold standard investigation for Coeliac?

A

Upper GI endoscopy and distal duodenal biopsy

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5
Q

What is the gold standard investigation for food/drug allergy?

A

Double-Blind Oral Challenge

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6
Q

What is the gold standard investigation for breast cancer?

A

Histopathology

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7
Q

What is the first line treatment for Hospital-Acquired Pneumonia?

A

Ciprofloxacin + Vancomycin

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8
Q

What is the treatment for severe HAP?

A

Tazocin + Vancomycin

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9
Q

What is the treatment for aspiration pneumonia?

A

Tazocin + Metronidazole

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10
Q

What is the treatment for CURB 0/1 CAP?

A

Amoxicillin

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11
Q

What is the treatment for CURB 2 CAP?

A

Amoxicllin

Clarithromycin

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12
Q

What is the treatment for CURB 3-5 CAP?

A

Co-Amoxiclav

Clarithromycin

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13
Q

What is the first line management for Minimal Change disease?

A

Steroids

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14
Q

What is the second line management for Minimal Change Disease?

A

Cyclosporin

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15
Q

What is the first line agent for CMV?

A

Ganciclovir

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16
Q

How is EBV managed?

A

Supportive

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17
Q

How is VZV managed?

A

Aciclovir

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18
Q

How is HSV managed?

A

Aciclovir

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19
Q

What is the first line management for myeloma?

A

Bortezomib

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20
Q

How is Salmonella treated?

A

Ceftriaxone

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21
Q

How is Campylobacter treated?

A

Erythromycin/Ciprofloxacillin

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22
Q

How is Listeria treated?

A

Ampicillin

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23
Q

How are Entamoeba histolytica/Giardia lamblia treated?

A

Metronidazole

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24
Q

How is Cryptosporidium Parvum managed?

A

Paromomycin

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25
Q

When would you consider transfusing red blood cells?

A

<70 if asymptomatic

<80 if symptomatic

26
Q

How is Dengue Fever managed?

A

Supportive

27
Q

How is DKA managed?

A

A to E
0.9& Saline
Fixed rate IV insulin after fluids
Monitor Glucose & K+

28
Q

How is HHS managed?

A

A to E
0.9% Saline
Fixed rate IV Insulin

29
Q

How would you manage a surgical wound infection with Staph a?

A

Fluclox

30
Q

How is syphilis treated?

A

Single dose IM Benzylpenicillin

31
Q

How is TB treated?

A

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol

32
Q

How is cryptococcal meningitis treated?

A

Amphotericin B

33
Q

How would you manage MGUS/Smouldering Myeloma?

A

No treatment needed

34
Q

How would you treat gonorrhoea?

A

IM Ceftriaxone

35
Q

What are the 5 steps for suspected Diabetes Insipidus?

A 
Glucose
K
Ca
Plasma/Urine Osmolality
8 Hour water deprivation test
36
Q

How is nephrogenic diabetes insipidus treated?

A

Thiazide Diuretics

37
Q

What is the only curative treatment for myelofibrosis?

A

Stem Cell Transplant

38
Q

How is HIV treated in pregnancy?

A

Zidovudine (NRTI)

39
Q

How is Digoxin toxicity treated?

A

Digibond

40
Q

How would you treat hypokalaemia 3.0-3.5?

A

Oral KCl

41
Q

How would you treat Hypokalaemia <3.0?

A

IV KCl

42
Q

When would you treat Hyperkalaemia?

A

> 5.5 and ECG changes

>6.5 regardless

43
Q

How would you treat Hyperkalaemia?

A 
Calcium Gluconate
Dextrose + Insulin 
Nebulised Salbutamol
Maybe Calcium Resonium
Treat Cause
44
Q

How would you treat Carcinoid Syndrome?

A

Octeotride (Somatostatin Analogue)

45
Q

Which factors’ synthesis is inhibited by Warfarin?

A

2,7,9,10

C,S,Z

46
Q

Which factors does heparin inhibit?

A

Thrombin

9,10,11

47
Q

How would you manage someone with Vitamin K Deficiency who is acutely haemorrhaging?

A

Fresh Frozen Plasma

48
Q

How might Myasthenia Gravis be treated?

A

Neostigmine

49
Q

Which drugs may be used to treat small/medium vessel vasculitides?

A

Corticosteroids

Cyclophosphamide

50
Q

How is Hodgkin’s Lymphoma treated?

A 
ABVD
Adriamycin
Bleomycin
Vinblastine
Dacarbazine
51
Q

How is chronic granulomatous disease treated?

A

IFN-gamma

52
Q

How is AML treated?

A

Daunorubicin

Cytarabine

53
Q

Which drug targets diseases with a (9;22) translocation?

A

Imatinib

54
Q

How is Burkitt’s Lymphoma treated?

A

Rituximab (Anti-CD20)

55
Q

How is Acute Rheumatic fever treated?

A

Benzylpenicillin

56
Q

Name one agent which may be used in the treatment of Sideroblastic Anaemia?

A

Pyridoxine

57
Q

How is Addison’s Treated?

A

Hormone replacement

58
Q

How is Haemochromatosis treated?

A

Venesection

Desferrioxamine

59
Q

How is Wilson’s treated?

A

Zinc + Trientine > Penicillamine

60
Q

How might Multiple Sclerosis be treated?

A

Corticosteroids
Interferon Beta
Natalizumab

61
Q

How might you manage Goodpasture’s?

A

Plasmapheresis

62
Q

How would you manage Kostmann Syndrome?

A

Colony stimulating factor

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