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Pharm > Malignant Hyperthermia (MH) > Flashcards

Malignant Hyperthermia (MH) Flashcards

0
Q

Not MH triggers

A 
IV anesthetics (Propofol)
Opiates
Non-depolarizing muscle relaxants
Ketamine
Sedatives and tranquilizers
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1
Q

Known chemical MH triggers

A

Forane (Isoflurane)
Sevoflurane
Suprane
Anectine (Succinylcholine)

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2
Q

Specific clinical signs of MH

A

Muscle Rigidity
Dramatically increased CO2 production
Rhabdomyolysis
Profound hyperthermia

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3
Q

Non-Specific clinical signs of MH

A

Tachycardia
Tachypnea
Acidoses (both resp & metabolic)
Hyperkalemia

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4
Q

Dantrolene

A

Dantrium

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5
Q

Treatment of acute MH

A

D/C anesthetic gas
100% hyperventilate
1-2mg/kg of bicarb
Dantrolene dose of 2.5mg/kg IV push + PRN
Cool pt
NO Calcium Channel Blockers
Monitor coagulation and electrolytes for (DIC)

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6
Q

Dantrolene (Dantrium) dose for acute MH

A

2.5mg/kg IV push and repeat PRN

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Pharm (10 decks)

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