malignant bone tumoues Flashcards

(30 cards)

1
Q

osteosarcoma

A

malignant bone tumour that produces bone

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2
Q

symptoms of osteosarcoma

A

constant pain
worse at night
fatigue
weight loss

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3
Q

treatment for osteosarcoma

A

chemotherapy

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4
Q

age of those with osteosarcoma

A

young adults

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5
Q

where is osteosarcoma found

A

commonly the knee

spread haematogenously

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6
Q

chromosome translactchondrosarcoma

A

cartilidge producing primary bone tumour

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7
Q

symptoms of chondromsarcoma

A

sciatica
back pain
bladder pain
unilateral oedema

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8
Q

where is the chondrosarcoma most commonly seen

A

proximal femur and pelvis

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9
Q

who is affected by chondrosarcoma

A

older patients- around 45

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10
Q

treating chondrosarcoma

A

symptsurgery- resection

no chemo or radio

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11
Q

chondrosarcoma- spread

A

very large and slow to spread

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12
Q

ewings syndrome

A

small round blue cell tumour

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13
Q

causes of ewings syndrome

A

chromosome translocation between chromosome 11 and 22- weings sarcoma gene on 22

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14
Q

symptoms of ewings sarcoma

A

fever
raised inflammatory markers
warm swellings at site

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15
Q

where ewings syndrome effects

A

long bones

femur

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16
Q

who ewings syndrome effects

17
Q

treating ewings sydnrome

A

chemo or radio

18
Q

how ewings syndrome looks

A

onion skin appearance

19
Q

lymphoma

A

cancer of the round cells of the lymph system and macrophages

20
Q

symptoms of lymphoma

A
lymphadenopathy
night sweats 
weight loss
fatigue
fever
21
Q

treating lymphoma

A

non aggressive- wait and watch
agrresive- chemo
hodhkins- radio

22
Q

myeloma

A

clonal proliferation of abnormal plasma cells wwhich arise from bone marrow

23
Q

symptoms of myeloma

A
anaemia
weight loss
fatigue
bone pain
back pain
24
Q

age of someone with myelona

25
types of myeloma
plasmacytoma | multiple myeloma
26
treatment for myleoma
plasmacytoma- radio | multiple myeloma- chemo
27
diagnosing myeloma
plasma protein electrophoresis | early morning urine collection for bence protein assay
28
myeloma on bone scan
no mets may be sseen as lack osteoblastic response
29
worst prognosis
ewings syndrome
30
bone mets examples
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