Male Urethral Stricture Flashcards

1
Q

What is the mucosal histology of the posterior urethra, anterior urethra, and fossa navicularis?

A

posterior: transitional epithelium
anterior: pseudostratified columnar epithelium

fossa navicularis: stratified squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are presenting features of urethral stricture?

A

decreased urinary stream
incomplete bladder emptying
UTI
epididymitis
rising PVR
decreased force of ejaculation
dysuria
spraying

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What important factors are there to consider for positioning during urethral stricture repair?

A

high lithotomy
avoid pressure on calf muscles, peroneal nerve and ulnar nerve
use SCDs to prevent VTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

After a urethral repair, what follow up imaging is recommended?

A

urethrography or VCUG 2-3 weeks after
replace catheter if persistent leak to avoid inflammation, urinoma, abscess, and/or urethrocutaneous fistula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Clinicians SHOULD include urethral stricture in ddx of men who present with which symptoms?

A

GUIDELINE STATEMENT 1

decreased urinary stream
incomplete emptying
dysuria
UTI
rising PVR

*stricture characteristics (length, diameter, duration of obstruction) lend to sxs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Risk factors for forming urethral stricture?

A

hypospadias surgery
urethral catheterization or instrumentation
traumatic injury
transurethral surgery
prostate cancer
idiopathic
inflammatory disorder (LS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What non invasive measures can be performed initially in a patient with suspected urethral stricture?

A

GUIDELINE STATEMENT 2

H&P
UA
Uroflow
PVR

*AUA-SS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What evaluations would be next step to confirm diagnosis of urethral stricture after non-invasive measures?

A

GUIDELINE STATEMENT 3

Cysto
RUG
VCUG
US urethrography
MRI (can provide detail in certain cases, e.g diverticulum, fistula, cancer)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In planning non-urgent intervention for known stricture what must be determined:

A

GUIDELINE STATEMENT 4

length and location

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Patients with symptomatic stricture including urinary retention or need for catheterization, may undergo which procedures urgently?

A

GUIDELINES STATEMENT 5

DVIU
SPT
GUIDELINE STATEMENT 6

surgeons may place SPT prior to definitive urethroplasty depending on CIC Or foley

“urethral rest” 4-12 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is considered a short bulbar urethral stricture? What is an initial treatment options?

A

GUIDELINE STATEMENT 7

< 2 CM

DVIU or dilation

urethroplasty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What types of endoscopic treatment may be offered for urethral stricture? When may catheter be removed if uncomplicated procedure?

A

GUIDELINE STATEMENT 8

Dilation

DVIU

GUIDELINE STATEMENT 9

72 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

For pts who are not candidates for urethroplasty, who have undergone DVIU, clinicians may recommend what at home activity?

A

GUIDELINE STATEMENT 10

self-catheterization to maintain temporary urethral patency

ranging daily to weekly > 4 mo reduces recurrence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

For recurrent anterior urethral strictures, after failed dilation/DVIU, what management is recommended?

A

GUIDELINE STATEMENT 11

Urethroplasty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

For surgeons who do not perform urethroplasty, what is an option?

A

GUIDELINE STATEMENT 12

refer to surgeon with expertise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Initial treatment of metal or fossa navicularis strictures?

A

GUIDELINE STATEMENT 13

dilation or meatotomy

as long as not associated with previous hypo repair, prior failed endoscopic treatment, previous urethroplasty, or LS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Recurrent metal or fossa navicularis strictures, should be treated with?

A

GUIDELINE STATEMENT 14

urethroplasty

*or associated with hypospadias or LS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Penile urethral strictures should be treated with?

A

GUIDELINE STATEMENT 15

urethroplasty due to high recurrence rates with endoscopic tx

19
Q

Patient with bulbar strictures > 2 cm should be treated with?

A

GUIDELINE STATEMENT 16

urethroplasty due to low success rate of DVIU/dilation

20
Q

Multi-segment strictures may be reconstructed utilizing what surgical technique and material?

A

GUIDELINE STATEMENT 17

One stage or multistage

oral mucosal graft, penile fasciocutaneous flap or combo

21
Q

what is a long term alternative for severe complex or length strictures?

A

GUIDELINE STATEMET 18

perineal urethrostomy

*recurrent complex anterior stricture, advanced age, medical co-morbidities, extensive LS, numerous failed urethroplasty, and patient choice

22
Q

What is the first choice when using grafts for urethroplasty? What materials/donor sites shouldn’t be used?

A

GUIDELINE STATEMENT 19

oral mucosa

*inner cheek, be careful of salivary gland

GUIDELINE STATEMENT 20

should not perform substitution urethroplasty with allograft, xenograft, or synthetic materials

GUIDELINE STATEMETN 22

do not use hair-bearing skin

23
Q

What technique should not be performed by a single-stage?

A

GUIDELINE STATEMENT 21

tubularized graft urethroplasty

due to high risk of restenosis

24
Q

After pelvic fracture urethral injury (PFUI), planning a delayed repair, what testing should be done pre-operaitvely?

A

GUIDELINE STATEMENT 23

RUG + VCUG

and/or

Retrograde + Antegrade Cystoscopy

Other adjunctive tests include: pelvic CT or MRI to assess proximal extent of injury

25
Q

After PFUI with urethral obstruction/obliteration due to pelvic fracture, what type of repair should be done? When?

A

GUIDELINE STATEMENT 24

delayed urethroplasty

GUIDELINE STATMENT 25

only after major injuries have stabilized and patients can be safely positioned

26
Q

What are treatment options for bladder neck contracture after endoscopic prostate procedure?

A

GUIDELINE STATEMENT 26

Dilation

Bladder neck incision

transurethral resection of bladder neck contracture

27
Q

What are treatment options for bladder neck contracture post prostatectomy for vesicourethral anastomotic strictures? What is performed for recalcitrant stenosis?

A

GUIDELINE STATEMENT 27

dilation

vesicourethral incision

transurethral resection

*lower success in cases of radiation

GUIDELINE STATEMENT 28

open reconstruction of bladder neck

*may need sphincter

28
Q

Men who perform chronic CIC with strictures may be offered which treatment?

A

GUIDELINE STATMENT 29

urethroplasty

when causing problems with CIC

29
Q

If alternative pathology is suspected in the urethra?

A

GUIDELINE STATEMENT 30

biopsy

for LS or suspected urethral cancer

30
Q

Urethroplasty in a patient with LS, what is important to remember?

A

GUIDELINE STATEMENT 31

do not use genital skin

31
Q

Follow up of urethral strictures?

A

GUIDELINE STATEMENT 32

monitor for symptomatic recurrence following dilation, DVIU, and urethroplasty

utilize AUA SS, uroflow, pvr

*can occur at any time

*risks for recurrence failed tx, tobacco, DM, increasing length, LS, hypo. graft/flap

32
Q

AUA SS includes which elements, plus bother:

A
33
Q

In the setting of a prior urethral stricture dilation, with pelvic trauma/fracture and blood at the meatus, what is the significance of a butterfly hematoma?

A

urethral injury

contained in Colles’ facia

superiorly the extravasation can extend to clavicles where Scarpa’s facies the abdominal extension of Colles’ facia attaches

34
Q

Describe endoscopic realignment in patient with urethral disruption for whom you have placed a SPT:

A

2 surgeons

flexible/rigid cystoscopy via urethra and SPT to try to pass a wire across the defect with fluoroscopy

prolonged attempts should not be performed

35
Q

Describe posterior urethral stricture repair?

A
  1. high lithotomy
  2. lamba incision in perineum
  3. divde bulbospongiosus muscle
  4. circumferentially mobilize urethra distally to penoscrotal junction and proximally to obliterated segment of the urethra
  5. excise intervening scar between distal urethral segment and apex of prostate
  6. identify prostatic apex, if cannot reach → separate corpus cavernosum in midline, if cannot reach → perform pubectomy (give additional length), if still cannot reach → re-route urethra under ones side of corpus cavernosum
  7. Tension free anastomosis
  8. Foley
36
Q

Etiologies of low Qmax and elevated PVR in a male?

A

NGB

BPH

urethral stricture

37
Q

List risks of urethroplasty:

A

bleeding
infection
DVT
nerve damage (peroneal)
rectal injury
testicular injury
stricture recurrence
ED
EjD
urethrocutaneous fistula formation
penile chordee
altered penile sensation
post void dribbling
mouth scarring (buccal)
obstruction of salivary duct (buccal)

38
Q

Describe a bulbar EPA urethroplasty:

A
  1. vertical midline perineal incision
  2. dissect through Colles’ facia
  3. divide bulbospongiosus muscle
  4. circumferentially mobilize the urethral distally to penoscrotal junction and proximally towards membranous urethra after dividing central tenon
  5. ID stricture by cysto
  6. excise urethral stricture
  7. spatulate proximal and distal ends of urethral 1 cm on each side
  8. Distal spatulate ventrally
  9. proximal spatulate dorsally
  10. anastomosis with absorbable interrupted
  11. foley
  12. close
39
Q

Describe substitution urethroplasty with buccal mucosa:

A
  1. vertical midline perineal incision
  2. dissect Colles’ facia
  3. sharply divide bulbospongiosus muscle
  4. ID stricture via cysto
  5. excise urethral stricture
  6. spatulate urethra dorsally 1 cm on each side, measure defect
  7. harvest buccal mucosa
  8. fenestrate for dorsal, don’t fenestrate for ventral
  9. lay graft on corporal bodies an secure with absorbable suture
  10. close lateral sides of buccal graft to native urethra with absorbable suture
  11. test anastomosis for water tightness with irrigation in urethra
  12. foley
  13. close
40
Q

What is blood supply to penis?

A

Internal iliac artery

Internal pudendal artery

Common penile artery
Bulbourethral artery → corpus spongiosum
Dorsal artery of penis → glans
Cavernosal artery → corpus cavernosa
Circumflex artery → crus of corpus cavernosa

41
Q

What is blood supply to urethra?

A

dual blood supply

Proximal: bulbourethral artery → proximal corpus spongiosum

Distal: dorsal artery of penis → via communicators to glans penis

42
Q

What questions do you ask a patient with suspect urethral stricture?

A

History of perineal/scrotal trauma

prior UTIs/STIs

Sexually active, ED, EjD

length of time of sxs

episodes of retention

hx of catheterization or difficulty with cath

hematuria

AUA SS

43
Q

What is recurrence rate of DVIU at one year?

A

50% in 1 year

Follow with AUA SS, uroflow/pvr, cysto, RUG