male reproductive system Flashcards
organisation of testis into
Tubular component and interstitial components
tubular components
sertoli cells and germ cells
interstitial components
leydig cells and capillaries
sertoli cells
support the development of germ cells from spermatogonia which undergoes meiosis to become primary spermatocytes and then mitosis to become secondary spermatocytes then they become spermatids and finally spermatozoa in the epididymis
Luteinising hormone
stimulates testosterone secretion, testosterone has a negative feedback affect on the hypothalamus and the anterior pituitary and reduces secretion of GnRH and LH
FSH stimulates
spermatogenesis along with testosterone
sertoli cells
in the seminiferous tubules secrete androgen binding globulin and inhibin, inhibin has a negative feedback affect on the anterior pituitary reducing secretion of FSH
fertilisation occurs in the
ampulla of the fallopian tube
pre-fertilisation events
- cervical mucous becomes thinner which allows the easier passage of sperm
- muscular contractions of the uterus and fallopian tubes assist the movement of sperm
the sperm then reaches the egg in the
ampules of the fallopian tube, the egg is covered in a layer of cells called the corona radiate which the sperm must penetrate to reach the zona Pellucida, capacitation then has to occurs which is followed by a reaction in which the acrosome of the sperm releases digestive enzymes allowing the sperm to penetrate the egg
the sperm which has penetrated the zona pellucida then
fertilises the egg, a single seem attaches to the egg cell membrane and the outer membranes fuse
this causes
changes in the egg cell membrane preventing other sperm from attaching, the egg then produces chemicals which pushes other sperm away from the egg and causes the hardening of the bona pellucida
the final step of fertilisation involves
the fusion of the sperm pro-nucleus with the egg pro-nucleus (which contains 23 chromosomes each)
