Male Reproductive System Flashcards

1
Q

In what structure does spermatogenesis occur?

A

Seminiferous tubules

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2
Q

What do Leydig cells make primarily? What hormone from the anterior pituitary are they sensitive to?

A

They make testosterone, sensitive to LH from the AP

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3
Q

Name seven things that Sertoli cells do.

A
  1. Make ABP.
  2. Make inhibin.
  3. Aromatize androgens (turn testosterone into estogen)
  4. Release trophic products.
  5. Increase LH receptors on Leydig cells (through release of trophic products).
  6. Promote cell division to increase the number of spermatogonia.
  7. Assist in sperm development.
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4
Q

Which cell division event in spermatogenesis begins in fetal life and continues throughout the male life span?

A

Mitosis that generates spermatogonia

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5
Q

Which cell division event in spermatogenesis begins in puberty?

A

Meiosis

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6
Q

Which meiosis stage are primary spermatocytes in? What about secondary spermatocytes?

A

Primary spermatocytes are in meiosis 1, secondary spermatocytes are in meiosis 2.

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7
Q

Have spermatids completed meiosis?

A

Yeah

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8
Q

In what structure does final maturation of spermatids occur?

A

Epididymis

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9
Q

What is a spermatozoa?

A

Sperm with maturing tails and acrosomes

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10
Q

What is a spermatocyte?

A

Mature sperm

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11
Q

What are the five stages of sperm development?

A

Stage 1: Spermatogonia undergo mitosis to expand the population, then they undergo meiosis to become primary, then secondary spermatocytes, and finally spermatids.
Stage 2: Spermatid moves towards the seminal canal, tail begins to develop.
Stage 3: Tail continues to develop. Spermatids are clustered in the center of the seminal canal.
Stage 4: Head becomes more streamlined.
Stage 5: Mature spermatocytes in the seminal canal are moved by gentle fluid flow towards the epididymis where the tails undergo maturation for motility.

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12
Q

What is involved in “final sperm maturation” in the epididymis? (name 4 things)

A
  1. Maturation of the motors and mitochondria in the sheath.
  2. Maturation of the acrosome.
  3. Gain the ability to bind to the zona pellucida.
  4. Cytoplasm volume decreases.
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13
Q

Semen production by the accessory sex glands is ________-dependent.

(hint: it is a hormone)

A

testosterone

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14
Q

60% of the seminal vesicle secretions are made up of _________ and _________.

A

fructose and prostaglandins

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15
Q

The early stages of sperm production are ________ independent.

A

androgen

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16
Q

How long does it take for a spermatogonia to become a mature sperm?

A

74 days

17
Q

What will happen to a non-motile sperm?

A

Death

18
Q

What protein regulates sperm motility? Where is it located?

A

CatSper calcium protein (a Ca2+ channel). Located in the main part of the tail - the mitochondrial sheath.

19
Q

________ sensors in the head of the sperm help direct ultimate motility towards the ovary.

A

Olfactory

20
Q

How many million spermatocytes are in one mL of semen from a healthy, fertile male?

A

100 million

21
Q

How fast do sperm swim?

A

3mm/min

22
Q

What temp is needed for normal sperm production in the testicles?

A

32 Celsius

23
Q

What sperm count is considered infertile?

A

Less than 20 million per mL of semen

24
Q

What systems innervate the male reproductive system?

A

Sympathetic and parasympathetic branches of the ANS, somatic sensory, and motor nerves.

25
Q

Describe nerve stimulation events during an erection.

A

Parasympathetic stimulation, sympathetic inhibition of the nerves that control blood flow to the penis.

26
Q

_______ _______ is a key mediator in becoming erect/maintaining an erection. It increases ______ production in vascular smooth muscle cells and causes vasodilation.

A

Nitric oxide causes cGMP production in smooth muscle cells –> vasodilation.

27
Q

What event precedes ejaculation? It is characterized by the movement of semen into the proximal urethra.

A

Emission

28
Q

How is emission produced?

A

Peristaltic contractions of the vas defrens, seminal vesicles, and prostate. Also accompanied by constriction of the internal sphincter of the urinary bladder.

29
Q

What branch of the nervous system controls emission?

A

Sympathetic branch of the ANS

30
Q

What triggers the reflex action of ejaculation?

A

The entry of semen from the proximal urethra into the bulbous urethra.