Male Reproductive Physiology Flashcards
Countercurrent health exchange
Constant testicular temperature
Cools arterial blood with venous blood
Pamniform plexus
What factors affect testicle temperature
(Need to be less than body)
Hyperthermia
Mumps
Viral infection
Endocrine factors affecting spermatogenesis
Anabolic steroids
Reduction in gonadotropin sand androgens
Environmental factors affecting spermatogenesis
Occupation - car industry, welding, plastic manufacture
Radiation
Smoking
Alcohol
Medicines affecting spermatogenesis
Some anti-hypertensives
Some anti-depressants
Where is sperm produced
Seminiferous tubules
Where is inhibit B secreted
Sertoli cells
Sertoli cell functions (7)
1) Form blood seminiferous tubule barrier
2) Active transport of molecules to blood
3) Maintain micro environment
4) Physical movement of developing sperm towards lumen
5) Provision of nutrients to sperm
6) Support for spermiation
7) Secretion of inhibin B
Endocrine regulation
GnRH from hypothalamus
➡️ FSH and LH
➡️ Androgen binding protein
↘️ Leydig cells ➡️ Testosterone ➡️ Sertoli cells
↘️ Secondary Sexual Characteristics