Male Reproduction Flashcards

1
Q

Where does spermatogenesis occur?

A

seminiferous tubules

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2
Q

What do the Sertoli cells do?

A

provide nutrient environment for the production of sperm

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3
Q

What cells produce testosterone?

A

cells of Leydig

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4
Q

What hormone stimulates cells of Leydig?

A

LH

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5
Q

What hormone stimulates sertoli cells?

A

FSH

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6
Q

How to sertoli cells utilize testosterone?

A

After testosterone is released from cells of Leydig if diffuses across the blood/testes barrier to reach Sertoli cells which secrete an antigen-binding protein which keeps testosterone local

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7
Q

What do the sertoli cells inhibit?

A

can release inhibin which feedbacks to the anterior pituitary to inhibit the release of FSH

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8
Q

How many spermatozoa does one spermatogonia produce?

A

one spermatogonia produces 4 spermatozoa

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9
Q

What stimulates penile erection? Parasympathetic or sympathetic?

A

parasympathetic via NO; opposed by sympathetic (alpha-1)

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10
Q

At birth, how many eggs are contained in the ovary? How many mature to ovulation?

A

2-4million eggs in meiotic arrest; 400 mature to ovulation

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11
Q

What is the difference between male and female germ cells?

A

A female is born with all of the germ cells she will ever have while the male is constantly producing more germ cells

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12
Q

What are the four stages of the development of the oocyte?

A
  1. oogonia
  2. primary oocyte
  3. secondary oocyte (after puberty)
  4. ovum
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13
Q

The female gamete after ovulation and prior to fertilization is?

A

secondary oocyte

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14
Q

When is the oogonia present?

A

fetal life

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15
Q

when do oogonia arrest and become primary oocytes?

A

6 months postnatal

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16
Q

What is contained in the first polar body?

A

23 chromosomes, 2 chromatids

17
Q

In female reproduction,n what does FSH stimulate?

A

granulosa cells

18
Q

In female reproduction, what does LH stimulate?

A

Thecal cells

19
Q

What do thecal cells synthesize?

A

androgens

20
Q

what do granulosa cells synthesize?

A

convert androgens to estrogen

21
Q

What is a rate limiting step in the production of progesterone and estradiol?

A

LH needs to stimulate cholesterol desmolase

22
Q

How does progesterone act on the uterus?

A

increases secretions and decreases contractility

23
Q

How does estradiol act on the uterus?

A

increases contractility and cell proliferation/growth

24
Q

What dominates the follicular phase of menses?

A

estradiol

25
Q

What dominates the luteal phase of menses?

A

progesterone

26
Q

Does prolactin stimulate the secretion of another hormone?

A

no!