Male Repro Flashcards
What function does the epididymis have?
Storage, maturation, transport of sperm.
Sperm becomes fully motile after travelling through epididymis.
Maintains inactivity through H+ production.
What function does the Vas deferens have?
Sperm transport and has an enlarged ampulla for storage.
What does the seminal vesicle produce?
60% of fluid in semen Fructose Prostaglandins for cervix. Fibrinogen for coagulation Seminogelin - suppresses motility of coagulated sperm.
What function does the prostate have?
Secretes milky white fluid:
Prostatic acid phosphatase
Profibrinolysin (dissolved coagulated sperm)
HCO3 which neutralized acidic cervix.
PSA hydrolyzes seminogelin increasing sperm motility
Converts 90% testosterone to DHT by 5 alpha reductase to regulate prostate growth.
What does 5alpha-reductase do and where is it produced?
Produced by the prostate converting 90% of testosterone into DHT for regulation of prostate growth.
What does the bulbourethral gland do?
Secretes lubricative mucus into the vagina.
What function does LH hormone have on the testes?
Acts on the Leydig cells by upregulated cholesterol desmolase to produce pregnenolone which is ultimately formed into testosterone.
What does Testosterone do in the testes?
Testosterone difuses into the sertolli cells where it will fascilitate spermatogenesis.
What can testosterone be converted to and by what enzymes?
Estradiol by aromatase
DHT in the prostate by 5alpha-reductase.
What provides feedback to arcuate nucleus producing GnRH?
Inhibited by testosterone, Estradiole, and DHT.
Testosterone inhibits GnRH release as well as LH release.
What function does FSH serve?
Activates sertoli cells to fascilitate spermatogenesis.
Upregulates Androgen binding protein = localizes test. for spermatogenesis.
Increases growth of Leydig cells.
Produces and secretes inhibin that inhibits FSH secretion.
What specifically inhibits the release of FSH and LH?
FSH is inhibited by inhibin made by sertoli cells.
LH is inhibited by Testosterone made in the Leydig cells.
what is spermatogenesis?
The response of GnRH leading to increased testosterone.
This leads to the two meitotic devisions leading to the formation of sperm.
What is spermiation?
The transfer of spermatazoa (Sperm) into the seminiferous lumen.
What is spermiogenesis?
The differentiation of spermatids into actual sperm through elongation and addition of the acrosomal cap.