Male GU Pharm Flashcards
Alpha 1 adrenergic receptor antagonists
Terazosin
Doxazosin
Tamsulosin
Silodosin
Alfuzosin
Alfuzosin adverse effect
QT prolongation
Tamsulosin and silodosin adverse effects
Reduced ejaculation and IFIS (complication during cataract surgery)
Terazosin and doxazosin adverse effects
Postural hypotension, dizziness, fatigue
Take before bed
Steroid alpha5 reductase inhibitors
Finasteride
Dutasteride
Finasteride blocks?
SAR-2
Dutasteride blocks?
SAR-1 and SAR-2
Don’t give finasteride Or dutasteride to who?
Pts who are also suffering from ED
How to treat both BPH and ED?
Tadalafil
It’s a PDE-5 inhibitor
ED drug with quickest onset
Avanafil
15 mins vs an hour
ED drug with longest duration of action
Tadalafil
36 hrs vs 4-5
Blue/blurry vision adverse effect of what drugs?
Sildenafil
Vardenafil
Avanafil
Tadalafil adverse effects
Back pain
Myalgia
Limb pain
Contraindication for PDE-5 inhibitors
Organic nitrates- extreme and dangerous hypotension
This can kill pts*****
PDE-1 agonist
Alprostadil
For ED, injection
Use in pts who cannot take other ED drugs