Male breast cancer Flashcards
What structures are in the male breast. What is significance?
Just ducts and terminal buds.
Therefore there are no lobular related pathologies (no lobular carcinoma, fibroadenoma)
Gynecomastia - non-neoplastic enlargement of epithelial and stromal elements. Behind the nipple. Can be normal in boys under 13 or men over 65
- Classic meds/conditions a/w gynecomastia?
- 3 types
- Spironolactone, psych meds, weed, cirrhosis, testicular cancer.
- Nodular - most common, flame shaped. can be painful, reversible
dendritic - chronic/fibrotic. Brandhes like a tree. Not painful
diffuse - looks like women’s breast , a/w estrogen therapy
When working with male breast, always get mammogram. (Although Wilmarie says that ACR now says you can get u/s first in males under 25).
- Name for fat person’s breasts
- pseudogynecomastia
- 2nd most common palpable breast mass in male (after gynecomastia)
Lipoma
Typical features of male breast cancer
Always ductal
usuallys spiculated mass
usually older man (average age >70)
2 big risk factors for male breast cancer
BRCA2 (2 is greater than 1)
Klinefelters
should someone who is transgender female getting hormone therapy get a screening mammogram?
No. But if they have a palpable mass, they should still be assessed.
three types of gynecomastia
- nodular (early gynecomastia of <1yr in duration)
- dendritic (the typical “flame shape”)
- diffuse glandular (associated with high dose estrogen therapy)
presentation of gynecomastia
soft tender, mobile subareolar mass
presenation of male breast cancer
nontender mass eccentric to the nipple
risk factors for male breast cancer
hereditary:
- BRCA1/BRCA2
- Klinefelter syndrome
- family hx of breast cancer in a first degree relative
other factors:
- hyperestrogenism
- advanced age
- history of chest radiation
- exogenous estrogen treatment
most common subtype of male breast cancer
IDC
always choose IDC if given a choice
