malaria protozoa Flashcards

1
Q

is there a vaccine for malaria

A

no

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2
Q

why is there a world wide resurgence

A

increased travel

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3
Q

what is the vector

A

anopheles mosquito vector

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4
Q

what is the protozoa

A

parasitic protozoa of genus plasmodium

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5
Q

how many countries are at risk of malaria transmission

A

106

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6
Q

where are 91% of malaria deaths

A

africa

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7
Q

how many cases are there per year

A

207 million

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8
Q

how many types of plasmodium parasite are there

A

five

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9
Q

describe

plasmodium Falciparum

A

mainly in africa
most common
most deaths world wide

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10
Q

describe

Plasmodium Vivax

A

mainly found in south east asia and south america
milder symptoms
infect liver for up to 3 years after = resulting replaces

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11
Q

describe

Plasmodium Ovale

A

fairly uncommon
found in west africa
can remain in liver for several years without symptoms

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12
Q

describe

Plasmodium Malariare

A

rare and usually found in africa

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13
Q

describe

Plasmodium Knowlesi

A

very rare and found in parts of south east asia.

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14
Q

how long is the incubation period of malaria

A

7-30 days

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15
Q

which type of malaria has lowest incubation period

A

Plasmodium Falciparum

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16
Q

which type of malaria has the longest incubation period

A

Plasmodium Malariae

17
Q

what can delay symptom appearance

A

antimalarial drugs

18
Q

a delay with what can product dormant liver parasites

A

P. ovale

p. Vivax

19
Q

a long delay of symptoms can result in

A

misdiagnosis or delayed diagnosis

20
Q

describe uncomplicated malaria

A

classical malaria attack 6-10 hours.
Cold phase
Hot phase
Sweating phase.

attacks every two days with “tertain” parasites and every three days with Guartan parasite.

21
Q

which malaria attacks every three days with guartan parasite

A

P. malariae

22
Q

which malaria attacks every two days with tertain parasites

A

p. Ovale
p. vivax
p. falciparum

23
Q

how do you diagnose malaria

A

need demonstration of parasite in the blood.

Blood smears thick and thin stained with haemotoxylin and eosin

additional lab findings: mild anaemia, thrombocytopenia, elevation of bilirubin and elevation of aminotransferases

24
Q

blood smears need to be stained with

A

heamotoxylin and eosin

25
Q

Describe

ATOVAQUONE PLUS PROGUANIL

A

not to be taken by pregnant or breast feeding

not for people with kidney problems

26
Q

describe DOXYXLINE

A

not for pregnant or breastfeeding,
not for children under twelve
or people who are sensitive to tetracycline
or liver problems

27
Q

describe

MEFLOQUINE

A

not for epilepsy, seizures, depression, mental health problems,
not for people with severe heart or liver problems

28
Q

describe CHLOROQUINE

A

rarely recommended now days

largely ineffective against most malaria parasite

29
Q

how would you treat mild p. falciparum

A

quinine then doxycycline or clindamycin

artemether with lumefantrine

or

atovaquone with prguanil

30
Q

treating severe p. falciparum

A

quinine IV
followed by quinine or artesunate tabs
requires refuel treatment and monitoring of complications

31
Q

how to treat other types of malaria

A

chloroquine tabs

primaquine after chloroquine