malaria protozoa Flashcards

1
Q

is there a vaccine for malaria

A

no

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2
Q

why is there a world wide resurgence

A

increased travel

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3
Q

what is the vector

A

anopheles mosquito vector

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4
Q

what is the protozoa

A

parasitic protozoa of genus plasmodium

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5
Q

how many countries are at risk of malaria transmission

A

106

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6
Q

where are 91% of malaria deaths

A

africa

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7
Q

how many cases are there per year

A

207 million

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8
Q

how many types of plasmodium parasite are there

A

five

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9
Q

describe

plasmodium Falciparum

A

mainly in africa
most common
most deaths world wide

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10
Q

describe

Plasmodium Vivax

A

mainly found in south east asia and south america
milder symptoms
infect liver for up to 3 years after = resulting replaces

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11
Q

describe

Plasmodium Ovale

A

fairly uncommon
found in west africa
can remain in liver for several years without symptoms

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12
Q

describe

Plasmodium Malariare

A

rare and usually found in africa

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13
Q

describe

Plasmodium Knowlesi

A

very rare and found in parts of south east asia.

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14
Q

how long is the incubation period of malaria

A

7-30 days

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15
Q

which type of malaria has lowest incubation period

A

Plasmodium Falciparum

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16
Q

which type of malaria has the longest incubation period

A

Plasmodium Malariae

17
Q

what can delay symptom appearance

A

antimalarial drugs

18
Q

a delay with what can product dormant liver parasites

A

P. ovale

p. Vivax

19
Q

a long delay of symptoms can result in

A

misdiagnosis or delayed diagnosis

20
Q

describe uncomplicated malaria

A

classical malaria attack 6-10 hours.
Cold phase
Hot phase
Sweating phase.

attacks every two days with “tertain” parasites and every three days with Guartan parasite.

21
Q

which malaria attacks every three days with guartan parasite

A

P. malariae

22
Q

which malaria attacks every two days with tertain parasites

A

p. Ovale
p. vivax
p. falciparum

23
Q

how do you diagnose malaria

A

need demonstration of parasite in the blood.

Blood smears thick and thin stained with haemotoxylin and eosin

additional lab findings: mild anaemia, thrombocytopenia, elevation of bilirubin and elevation of aminotransferases

24
Q

blood smears need to be stained with

A

heamotoxylin and eosin

25
Describe | ATOVAQUONE PLUS PROGUANIL
not to be taken by pregnant or breast feeding | not for people with kidney problems
26
describe DOXYXLINE
not for pregnant or breastfeeding, not for children under twelve or people who are sensitive to tetracycline or liver problems
27
describe | MEFLOQUINE
not for epilepsy, seizures, depression, mental health problems, not for people with severe heart or liver problems
28
describe CHLOROQUINE
rarely recommended now days | largely ineffective against most malaria parasite
29
how would you treat mild p. falciparum
quinine then doxycycline or clindamycin artemether with lumefantrine or atovaquone with prguanil
30
treating severe p. falciparum
quinine IV followed by quinine or artesunate tabs requires refuel treatment and monitoring of complications
31
how to treat other types of malaria
chloroquine tabs | primaquine after chloroquine