Malaria/Plasmodium Flashcards

0
Q

The sexual method of reproduction occurs in the definitive host (mosquito)

A

Sporogony

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1
Q

Formed in Man

A

Schizont

Gametes

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2
Q

Infective Stage in mosquito

A

Sporozoites

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3
Q

Exo-erythrocytic cycle happen in which organ?

A

Liver

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4
Q

A mature germ cell that is capable of functioning fertilization or conjugation and contains the haploid number of chromosomes of the somatic cell

A

Gamete

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6
Q

When is the ideal time to collect blood sample

A

Height of paroxysm

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7
Q

In which stage can you notice a ring form

A

Erythrocytic stage (young/immature trophozoite)

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8
Q

Macrogametocytes are for ______________ while microgametocytes are for _______________.

A

Macrogametocytes -> female

Microgametocytes -> male

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9
Q

The schizont that doesn’t rupture will become?

A

Gametes

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10
Q

The asexual method of reproduction occurs in intermediate host(man)

A

Schizogony

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10
Q

What does the mosquito ingest from the man?

A

Gametes

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11
Q

The schizont proliferates in the RBC, rupture and became?

A

Merozoites

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12
Q

It affects all ages of RBC

A

P.falciparum

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13
Q

The periodicity of its paroxysm happens every 72hrs (quartan)

A

P.malariae

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15
Q

The sporozoan body during schizogony which includes the period of initial growth to the complete splitting up of the nucleus with merozoite production

A

Schizont

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15
Q

Give the Tertian malaria’s

A

P.falciparum
P.vivax
P.ovale

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16
Q

It shows an enlarged and pale reticulocytes

A

P.vivax

P.ovale (w/ragged edges)

17
Q

The RBC’s appears to be normal in this Plasmodium

A

P.falciparum (smaller and numerous rings)

P.malariae

18
Q

It has a 6-32 merozoites

A

P.falciparum

19
Q

Give the number of merozoite in P.malariae

A

6-12 (rosette-shaped)

20
Q

It only affects adult RBC

A

P.malariae

21
Q

What can be seen in the trophozoite of a P.malariae?

A

Equatorial band-form

22
Q

Apique/accole shape trophozoites

A

P.falciparum

23
Q

Its trophozoite and schizont stage are not seen in peripheral blood smear

A

P.falciparum

24
It has a rounded gametocyte
P.vivas P.ovale (fimbriated) P.malariae
25
Give the shape of the P.falciparum gametocytes
Elongated; sausage-shaped; crescent-shaped
26
1) Schuffeners dots stippling :_________________ | 2) Maurer's dots stippling:__________________
1) P.vivax 2) P.falciparum P.ovale -> James dots P.malariae -> Ziemann's dots
27
Benign malaria's are _________
P.vivax | P.ovale
28
Quartan malaria __________
P.malariae
29
It causes blackwater fever
P.falciparum. Extensive Destruction of RBC.
30
Why is there an acute renal failure in P.falciparum?
Increase destruction of RBC
31
It has 70% frequency
P.falciparum
32
When is the height of paroxysm occurs?
When the cell ruptures and release merozoites
33
Can become active again/recrudesce.
P.falciparum | P.malariae
34
True relapse happen in?
P.vivax | P.ovale
35
Best staining result is achieved when using?
Giema's stain
36
Preferred for rapid diagnosis (quantitative)
Thick smear
37
Preferred for specie identification (qualitative)
Thin smear
38
First line of treatment for Malaria
Chloroquine
39
Treatment for those who have drug resistance to chloroquine
Mefloquine
40
Taken with atovaquone for the resistant strains for P.falciparum and P.vivax. Its action is ___________?
Proguanil; inhibiting enzyme dihydrofolate reductase
41
Treatment for persistent liver infection
Primaquine