Amoeba/Protozoa Flashcards by Hannah Gacott

The only amoeba that ingests WBC

Entamoeba gingivalis

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What is the smallest amoeba?

Endolimax nana

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It has a well defined glycogen mass w/ definite borders

Iodamoeba butschlii

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Treatment for E.histolytica and its mode of action

Metronidazole; Interferes w/ DNA replication

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Organ of locomotion of Acanthamoeba spp.

Acanthopodia

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Differentiate the E.histolytica from E.coli according to the chromatin body, type of pseudopod, number of nucleus, movement, and location of karyosome

E.histolytica: cigar shape chromatin body, clear finger-like pseudopod, directional movement, 4 nucleus and central karyosome

E.coli: splinter-like chromatin body, blunt pseudopod, sluggish movement, 8 nucleus (mature cyst) and peripheral karyosome

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Site of infection of intestinal E.histolytica

Small Intestine (excystation)
Large Intestine (trophozoite settle in its lumen)

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Site of infection of extraintestinal E.histolytica

Liver

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What is the aspirated material from the Amebic liver abscess?

Anchovy paste

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Difference of amebic dysentery and amebic colitis

Amebic dysentery: characterized by blood and mucus in the stool

mebic colitis: infection caused by amoebic presence in the intestine

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It causes flask-shaped ulcer in the colon?

Entamoeba histolytica

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What is the etiologic agent of E.histolytica infection?

Amoebic dysentery

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Common water contaminant

Entamoeba coli

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Sign that the organism is invasive and pathologic?

Blood in the cytoplasm

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Commonly found in Papua, New Guinea

Entamoeba polecki

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Similar to E.histolytica but is much smaller

Entamoeba hartmanni

Characterized by the absence of chromatin and clean cytoplasm

Endolimax nana

Commonly found in the mouth

Entamoeba gingivalis

Similar to E.nana (the only difference is that E.nana has 4 nucleus and this has only 1)

Iodamoeba butschlii

Flask-shaped ulcer is caused by?

E.histolytica

Amoeba that has no cystic stage?

E.gingivalis

Characterized by a basket nucleus and iodine cyst?

I.butschlii

Amoebas that has 1 nucleus?

E.polecki

I.butschlii

True pathogen’s amoebas

Naegleria fowleri

Acathamoeba sp.

What is the mode of entry of Naegleria fowleri?

Nasal cavity

Naegleria fowleri is acquired through?

Contaminated pools

Disease caused by Naegleria fowleri

Primary Amebic encephalitis

Treatment for True pathogens?

Amphotericin B

Difference between N.fowleri and Acanthamoeba?

N.fowleri has flagellated stage but Acanthamoeba is more resistant

How is Acanthamoeba transmitted?

Through contaminated lens care solution | Contaminated pools

Individuals who are affected by Acanthamoeba are mostly the?

Immunicompromised Contact lens wearer Those who experienced corneal trauma

Disease caused by Acanthamoeba?

GAE/Granulomatous Amebic Encephalitis (Type 4 Hypersensitivity Reaction) Types: Keratitis:contact lens Dermatitis:skin

This species is not found in tissues and can only be seen in culture

Naegleria fowleri

Morphology can be seen on wet preparation

Acanthamoeba spp.

Mortality for Acanthamoeba sp.

70% w/o CNS Involvement | 100% w/ CNS Involvement

Mode of entry of Acanthamoeba

May enterthrough lower respiratory tract or through ulcerated or broken skin

Two factors involved with Keratitis

Trauma | Contaminated water