Malaria

Question 0

define relapse in P. vivax and P. ovale

Answer 0

sporozite do not undergo immediate asexual replication “hypnozoites”, remain dormant in liver

Question 1

what is the vector for Plasmodium spp.?

Answer 1

Anopheles spp. namely An. donaldi, An. balabaciencis, An. Maculatus (Major in Malaysia)

An. gambiae and An. funestus (major in Africa)

An. leucosphyrus cracens : main vector for P. knowlesi in Malaysia

Question 2

define recrdescene in P. falcifwrum and P. malariae

Answer 2

parasite persist at low level in circulation, can not be detected.

Question 3

what is the stage of Plasmodium cycle that manifest the disease?

Answer 3

erythrocytic shcizony stage

Question 4

life cycle of plasmodium spp?

Answer 4

p. falciparum , P. ovale, P.vivax - 48 hours

P malariae : 72 hours

Question 5

define rosetting

Answer 5

shape of RBC is deformed, infected RBC adhere to unaffected RBC

Question 6

define cytoadherence

Answer 6

infected RBC adhere to endothelium of deep capillaries and post-capillary venules

Question 7

lethal malaria cause by….

Answer 7

P. falciparum

Question 8

syptoms of malaria

Answer 8

myalgia, fever, anorexia, nausea and vomiting. persist for 2-3 days before an acute paroxysm begin