Malabsorption Flashcards
Test for diagnosis of lactose intolerance
Hydrogen breath test
Most common symptoms of celiac disease
Diarrhea (most common)
Weakness/fatigue
Borborygmi
(bloating and cramps are common, severe abdominal pain is not)
Most common ages for celiac disease
10 to 40
Difference between celiac disease and non-celiac gluten sensitivity
Celiac = autoimmune
NCGS = not autoimmune, no hypersensitivity, no antibodies
Ethnicities most likely to have lactose intolerance
Blacks
Asians
Native Americans
This condition is known as asthma of the gut
Eosinophilic gastroenteritis
Skin changes seen in celiac disease
Dermatitis herpetiformis
Extraintestinal symptoms of celiac disease
Anemia
Osteopenia/porosis (vit D down)
Neurologic symptoms (vit D down)
Skin disorders
- dermatitis herpetiformis
Bleeding (vit K down)
True or false. Weight loss and nutritional deficiency is associated with lactose intolerance
False
(gut not getting attacked by immune system so no inflammation of small intestine leading to malabsorption)
Treatment for short bowel syndrome
Eat small meals of quickly absorbed/finely chopped foods
Complications of diseases of malabsorption
Vitamin K, A, D, E deficiencies
- may lead to osteoporosis
Anemia
- B12 deficiency
- Folate deficiency
- Iron deficiency
Dehydration
A patient with a wasting illness (weight loss) characterized by arthralgias, fever, and diarrhea likely has this rare disease
Whipple disease
Three antibodies present in celiac disease
Gliadin
Tissue transglutaminase
Endomysial - less important
A short bowel syndrome patient who had their ileum removed would have this deficiency
B12
Celiac disease is an inability to tolerate …
Gliadin
(a part of gluten)
Diagnostic tests for celiac disease
Tissue transglutaminase antibody test (order this first)
Antigliadin antibody test
(Maybe fecal fat test for fat malabsorption)
A short bowel syndrome patient who had their jejunum removed would have these deficiencies
Folate, calcium, iron
A patient with short bowel syndrome likely has a history of …
Surgery
Does a patient with lactose intolerance need to avoid lactose-containing medications?
No
They can tolerate up to two cups of milk per day, nowhere near that in meds
Symptoms of lactose intolerance
Pain, bloating, borborygmi, flatulence, nausea, diarrhea within a few hours of digestion (of milk or ice cream typically)
Age that eosinophilic gastroenteritis typically presents
30s to 50s
Symptoms with eosinophilic gastroenteritis
Abdominal pain
Weight loss
Vomiting
Diarrhea
Treatments for lactose deficiency
Reduce lactose in diet (don’t have to completely avoid)
Consider calcium and vit D supplementation
Lactase enzymes won’t hurt, may help
40% of patients with eosinophilic gastroenteritis have these co-occurring conditions
Asthma
Food allergies
Eczema
Rhinitis
