Major Hormones Flashcards
What are the target cells of the hypothalamus?
Anterior pituitary
Function: hypothalamus
Control release of anterior pituitary hormones
What hormones does the posterior pituitary release?
Vasopressin (ADH) and oxytocin
What are the target cells of vasopressin?
Kidney tubules
Function: vasopressin
Increase water reabsorption
What are the target cells of oxytocin?
Arterioles, uterus, and mammary glands
Function: oxytocin in arterioles
Vasoconstriction
Function: oxytocin in uterus
Increase contractility
Function: oxytocin in mammary glands
Cause milk ejection
What hormones does the anterior pituitary release?
Thyroid-stimulating hormone; adrenocorticotropic hormone; growth hormone; follicle-stimulating hormone; luteinizing hormone; and prolactin
Target cells: thyroid-stimulating hormone
Thyroid follicular cells
Function: thyroid-stimulating hormone
Stimulates T3 and T4 secretion
Target cells: adrenocorticotropic hormone
Zona fasciculata and Zona reticularis of adrenal cortex
Function: adrenocorticotropic hormone
Stimulate cortisol release
Target cells: growth hormone
Bone, soft tissues, and liver
Function: growth hormone in bones and soft tissues
Stimulate growth
Function: growth hormone in liver
Stimulate somatomedin secretion
Target cells: follicle-stimulating hormone
Females – ovarian follicles; males – seminiferous tubules
Function: follicle-stimulating hormone in females
Promote follicular growth and development; stimulate estrogen secretion
Function: follicle-stimulating hormone in males
Stimulate sperm production
Target cells: luteinizing hormone
Females – ovarian follicle and corpus luteum; males – interstitial cells of Leydig in testes
Function: luteinizing hormone in females
Stimulate ovulation, corpus luteum development, and estrogen and progesterone secretion
Function: luteinizing hormone in males
Stimulate testosterone secretion
Target cells: prolactin
Females – mammary glands; males – uncertain
Function: prolactin in females
Promote breast development and stimulate milk secretion
Function: prolactin in males
Uncertain
What hormones does the thyroid gland secrete?
T3 and T4
What hormone does thyroid gland C cells secrete?
Calcitonin
Target cells: T3 and T4
Most cells
Function: T3 and T4
Increase metabolic rate (essential for normal growth and nerve development)
Target cells: calcitonin
Bone
Function: calcitonin
Decrease plasma calcium concentration
What hormone(s) does the hypothalamus secrete?
Releasing and inhibiting hormones (TRH, CRH, GnRH, GHRH, GHIH, PRH, PIH)
What hormone does the Zona glomerulosa secrete?
Aldosterone
Target cells: aldosterone
Kidney tubules
Function: aldosterone
Increase sodium reabsorption and potassium secretion
What hormones does the Zona fasciculata and Zona reticularis secrete?
Cortisol and androgens
Target cells: cortisol
Most cells
Target cells: androgens
Females – bone and brain
Function: cortisol
Increase blood glucose from protein and fat stores and contributes to stress adaptation
Function: androgens
Responsible for pubertal growth super and sex drive in females
What hormones does the adrenal medulla secrete?
Epinephrine and norepinephrine
Target cells: epinephrine and norepinephrine
Sympathetic receptor sites across the body
Function: epinephrine and norepinephrine
Reinforces SNS, contributes to stress adaptation, and regulates blood pressure
What hormones does the endocrine pancreas secrete?
Insulin (beta cells), glucagon (alpha cells), and somatostatin (D cells)
Target cells: insulin
Most cells
Function: insulin
Promote uptake, use, and storage of absorbed nutrients
Target cells: glucagon
Most cells
Function: glucagon
Maintains nutrient levels in blood during postabsorptive state
Target cells: somatostatin
Digestive system and pancreatic islet cells
Function: somatostatin in digestive system
Inhibits digestion and absorption of nutrients
Function: somatostatin in pancreatic islet cells
Inhibits secretion of all pancreatic hormones
What hormones does the parathyroid gland secrete?
Parathyroid hormone (PTH)
Target cells: parathyroid hormone
Bone, kidneys, and intestine
Function: parathyroid hormone
Increase plasma calcium concentration, decreases plasma phosphate concentration, and stimulates vitamin D activation
What hormones does the ovaries secrete?
Estrogen and progesterone
Target cells: estrogen
Female sex organs, the body as a whole and bones
Function: estrogen in female sex organs
Promote follicular, secondary sexual characteristics, uterine, and breast growth
Function: estrogen in bone
Promote closure of epiphyseal plate
Target cells: progesterone
Uterus
Function: progesterone
Prepare for pregnancy
What hormone does the testes secrete?
Testosterone
Target cells: testosterone
Male sex organs, the body as a whole, and bones
Function: testosterone in male sex organs
Stimulates sperm production and sex drive, and governs development of secondary sexual characteristics
Function: testosterone in bone
Enhances pubertal growth spurt
What hormone is secreted by the ovaries AND testes?
Inhibin
Target cells: inhibin
Anterior pituitary
Function: inhibin
Inhibits secretion of FSH
What hormones does the placenta secrete?
Estrogen and progesterone
Target cells: estrogen and progesterone from placenta
Female sex organs
Functions: estrogen and progesterone from placenta
Maintain pregnancy and prepare breasts for lactation