Major Chemokines Flashcards

1
Q

CCL1

A

(CCR8) Monocyte recruitment and endothelial cell migration

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2
Q

CCL2

A

(CCR2) mixed leukocyte recruitment

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3
Q

CCL3

A

(CCR1, CCR5) mixed leukocyte recruitment

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4
Q

CCL4

A

(CCR5) T-cell, dendritic cell, monocyte, and NK recruitment; HIV coreceptor

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5
Q

CCL5

A

(CCR1,3,5) Mixed leukocyte recruitment.

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6
Q

CCL11

A

(CCR3) Eosinophil, Basophil and Th3 recruitment

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7
Q

CCL17

A

(CCR4) T-cell recruitment

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8
Q

CCL19

A

(CCR7) T-cell and dendritic cell migration into parafollicular zones of lymph nodes

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9
Q

CCL20

A

(CCR6) Th17 recruitment, DC positioning in tissue

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10
Q

CCL21

A

(CCR7) T-cell and dendritic cell migration into parafollicular zones of lymph nodes

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11
Q

CCL22

A

(CCR4) NK cell, T-cell recruitment

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12
Q

CXCL1

A

(CXCR2) Neutrophil Recruitment

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13
Q

CXCL5

A

(CXCR2) Neutrophil recruitment

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14
Q

CXCL8

A

(CXCR1,2) Neutrophil recruitment

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15
Q

CXCL10

A

(CXCR3,3B) Effector T cell recruitment

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16
Q

CXCL11

A

CXCR3, CXCR7) Effector T-cell recruitment

17
Q

CXCL12

A

(CXCR4) Mixed leukocyte recruitment; HIV coreceptot

18
Q

CXCL13

A

(CXCr5) B-cell migration into follicles; T follicular helper cell migration into follicles.

19
Q

CXCL14

A

Monocyte and dendritic cell migration.

20
Q

XCL1

A

(XCR1) T-cell and NK cell recruitment.

21
Q

CX3CL1

A

(Cx3CR1) t-cell, NK cell, and monocyte recruitment; CTL and NK cell activation.