Major Chemokines Flashcards
CCL1
(CCR8) Monocyte recruitment and endothelial cell migration
CCL2
(CCR2) mixed leukocyte recruitment
CCL3
(CCR1, CCR5) mixed leukocyte recruitment
CCL4
(CCR5) T-cell, dendritic cell, monocyte, and NK recruitment; HIV coreceptor
CCL5
(CCR1,3,5) Mixed leukocyte recruitment.
CCL11
(CCR3) Eosinophil, Basophil and Th3 recruitment
CCL17
(CCR4) T-cell recruitment
CCL19
(CCR7) T-cell and dendritic cell migration into parafollicular zones of lymph nodes
CCL20
(CCR6) Th17 recruitment, DC positioning in tissue
CCL21
(CCR7) T-cell and dendritic cell migration into parafollicular zones of lymph nodes
CCL22
(CCR4) NK cell, T-cell recruitment
CXCL1
(CXCR2) Neutrophil Recruitment
CXCL5
(CXCR2) Neutrophil recruitment
CXCL8
(CXCR1,2) Neutrophil recruitment
CXCL10
(CXCR3,3B) Effector T cell recruitment
CXCL11
CXCR3, CXCR7) Effector T-cell recruitment
CXCL12
(CXCR4) Mixed leukocyte recruitment; HIV coreceptot
CXCL13
(CXCr5) B-cell migration into follicles; T follicular helper cell migration into follicles.
CXCL14
Monocyte and dendritic cell migration.
XCL1
(XCR1) T-cell and NK cell recruitment.
CX3CL1
(Cx3CR1) t-cell, NK cell, and monocyte recruitment; CTL and NK cell activation.