Main Drugs Used Flashcards

1
Q

Adrenaline

indications

A

Croup (with stridor at rest)
Severe or life threatening bronchospasm (speaking in single words/ALOC/haemodynamic compromise)
Cardiac arrest
Anaphylaxis or severe allergic reaction
Bradycardia with poor perfusion (unresponsive to atropine or TCP)
Shock unresponsive to adequate fluid resus

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2
Q

Adrenaline

contraindications

A

Nil

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3
Q

Adrenaline

precautions

A

Current MAOI therapy
Hypertension
Hypovolaemic shock

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4
Q

Adrenaline

side effects

A
Tremors
Anxiety
Palpitations/Tachycardia
Hypertension
Pupil dilation
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5
Q

Adrenaline

Dosage for cardiac arrest

A

IV (ACP, CCP)
1mg every 3-5 minutes
No max dose

IO (CCP)
1mg every 3-5 minutes
No max dose

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6
Q

Adrenaline

Dosages for anaphylaxis or severe allergic reaction

A
IM (ACP1, ACP2, CCP)
300 mcg, repeat at 5 min
No max dose
NEB (ACP2, CCP) - for facial or tongue swelling
5mg single dose
IV/IO (CCP)
20-50 mcg, repeat at 1 min intervals
No max dose
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7
Q

Adrenaline

Dosages for severe to life threatening bronchospasm

A
IM (ACP1, ACP2, CCP)
300 mcg every 5 min
No max
IV/IO (CCP)
20-50 mcg every 1 min
No max
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8
Q

Aspirin

Indications

A

Suspected ACS

Acute cardiogenic pulmonary oedema

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9
Q

Aspirin

Precautions

A

Use of other anticoagulants (e.g. Warfarin)
Hx of GI bleed or peptic ulcer
Aortic aneurysm or other condition that may require surgery
Pregnancy

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10
Q

Aspirin

Side effects

A
GI bleed
Epigastric discomfort/pain
Nausea/vomiting
Gastritis
NSAID induced bronchospasm
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11
Q

Aspirin

Dosages

A

PO (ACP1, ACP2, CCP)
300mg single dose
Max dose 450mg

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12
Q

Aspirin

Onset, duration and half-life

A

Onset: approx 10 min
Duration: 1 week
Half life: 3.2 hours

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13
Q

Ceftriaxone

Indications

A

Suspected meningococcal septicaemia (with non blanching petechia and/or purpuric rash)

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14
Q

Ceftriaxone

Containdications

A

KSAR or hypersensitivity

Known anaphylaxis or severe allergic reaction to penicillin based drugs

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15
Q

Ceftriaxone

Precautions

A

Nil

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16
Q

Ceftriaxone

Side effects

A

Nausea/vomiting

Pain at IM injection site

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17
Q

Ceftriaxone

Adult dosages

A

IM (ACP1, ACP2, CCP)
1g single dose
Syringe preparation - reconstitute in 3.6mL of water in 10mL syringe
IV (ACP2, CCP) IO (CCP)
1g single dose - Slow push over 3-5 minutes
Syringe preparation - reconstitute in 10mL of water in 10mL syringe

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18
Q

Fentanyl

Indications

A
Significant pain
Autonomic dysreflexia (SBP >/= 160mmHg)
Sedation for maintenance of established LMA or ETT
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19
Q

Fentanyl

Contraindications

A

KSAR or hypersensitivity

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20
Q

Fentanyl

Precautions

A
Elderly
Hypotensive
Concurrent MAOI therapy
Respiratory tract burns
Respiratory depression/failure
Known narcotic addiction
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21
Q

Fentanyl

Side effects

A
Pinpoint pupils
Nausea/vomiting
Bradycardia
Hypotension
Drowsiness
Respiratory depression

(Not morphine) muscular rigidity - especially respiratory muscles

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22
Q

Fentanyl

Onset, duration, half-life

A

Onset: (IV)

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23
Q

Fentanyl

Dosages for significant pain and autonomic dysreflexia (ACP2 +)

A
IM (ACP1, ACP2, CCP)
>70 years 25mcg
Repeat at up to 50mcg every 5 min
Total max dose 100mcg
70 years 25mcg
Repeat at up to 25mcg every 5 min
Total max dose 100mcg
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24
Q

Glucagon

Indications

A

Symptomatic hypoglycaemia

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25
Q

Glucagon

Contraindications

A

KSAR or hypersensitivity

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26
Q

Glucagon

Precautions and side effects

A

Nil

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27
Q

Glucagon

Onset, Duration and Half-life

A

Onset: 4-7 min
Duration: variable
Half-life: 3-6 min

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28
Q

Glucagon

Dosages

A

IM (ACP1, ACP2, CCP)
1mg single dose
Reconstitute with 1mL water in 3ml syringe

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29
Q

Glucose 10%

Indications

A

Symptomatic hypoglycaemia

30
Q

Glucose 10%
Contraindications
Precautions
Side effects

A

Contras - nil
Precautions - hyperglycaemia
Side effects - nil

31
Q

Glucose 10%

Dosages

A

IV (ACP2, CCP) IO (CCP)
15g (150ml)
Repeat at 100ml boluses every 5 min until BGL >4mmol

32
Q
Glucose Gel
Indications 
Contraindications
Precautions
Side effects
A

Indications - symptomatic hypoglycaemia

Contras - age

33
Q

Glucose gel

Onset

A

Approx 10 min

34
Q

Glucose gel

Dosages

A

PO (ACP1, ACP2, CCP)
15g
Repeat once at 15 min of BGL less than 4mmol/L
Total max dose 30g

35
Q

GTN

Indications

A
Suspected ACS (with pain)
Acute cardiogenic pulmonary oedem
Autonomic dysreflexia (SBP >160)
Irukandji syndrome (SBP >160)
36
Q

GTN

Contraindications

A

KSAR

HR >150 or

37
Q

GTN

Precautions

A
Use of phosphodiestase inhibitors in last 48 hours
Cerebrovascular disease
Suspected inferior AMI
Risk of hypotension and/or syncope
Intoxication
38
Q

GTN

Side effects

A
Hypotension
Reflex tachycardia
Vascular headaches
Dizziness
Syncope
39
Q
GTN
Adult dosages (all indications)
A

Sublingual (ACP1, ACP2, CCP)
400mcg
Repeat at 5 min
No max

Also CCP IV infusion for suspected ACS

40
Q

Ipratropium Bromide

Indications

A

Moderate or severe bronchospasm

41
Q

Ipratropium Bromide

Contraindications

A

Age

42
Q

Ipratropium Bromide

Precautions

A

Glaucoma

43
Q

Ipratropium Bromide

Side Effects

A

Dilated pupils
Dry mouth
Palpitations

44
Q

Ipratropium Bromide

Onset, Duration, Half-life

A

Onset - 1.5-3 min
Duration - 4-6 hours
Half-life - 3 hrs

45
Q

Ipratropium Bromide

Dosages

A

NEB (ACP1, ACP2, CCP)
500mcg
Single dose

46
Q

Methoxyfleurane

Indications

A

Significant pain

47
Q

Methoxyfleurane

Contraindications

A

KSAR or hypersensitivity
Hx of malignant hyperthermia
Hx of significant renal or hepatic failure
Pt

48
Q

Methoxyfleurane

Precautions

A

ALOC

Intoxication or drug affected pt

49
Q

Methoxyfleurane

Side effects

A

ALOC
Cough
Renal/hepatic failure (following repeat high dose exposure)

50
Q

Methoxyfleurane

Onset, Duration, half-life

A

Onset - 1-3 min

51
Q

Methoxyfleurane

Dosages

A

Inhaled (ACP1, ACP2, CCP)
3ml
Repeat at 20 min

52
Q

Midazolam

Indications

A
Generalised/focal seizures
Avute behavioural disturbances (SAT 2 or more)
Sedation
- maintenance of LMA or ETT
- Procedures (TCP or cardioversion)
- Adjunct to opioid analgesia
- Ketamine emergence
- To facilitate safe assessment and treatment of agitated head injured patient
53
Q

Midazolam

Contraindications

A

KSAR or hypersensitivity

54
Q

Midazolam

Precautions

A
Severe respiratory distress in COPD
Myasthenia graves
MS
Use reduced dose for:
- elderly
- chronic renal failure
- congestive cardiac failure 
- shock
55
Q

Midazolam

Side effects

A

Hypotension

Respiratory depression - especially when used with other respiratory depressants

56
Q

Midazolam

Adult dosages for generalised or focal seizures

A

Nasal, IM (ACP1, ACP2, CCP)
>70 years 2.5mg
Repeat every 10 min
Total max, 10mg

IV/IO (CCP)
Same as above, every 5 min

57
Q

Morphine

Indications

A
Significant pain
Autonomic dysreflexia (SPB >160)
Sedation for maintenance of established LMA/ETT
58
Q

Morphine

Contraindications

A

KSAR or hypersensitivity

Renal failure

59
Q

Morphine

Precautions

A
Elderly
Hypotension 
Known narcotic addiction
Respiratory tract burns 
Respiratory depression/failure
Concurrent MAOI therapy
Cardiac chest pain
60
Q

Morphine

Side effects

A
Pin point pupils
Bradycardia
Hypotension
Nausea/vomiting
Drowsiness
Respiratory depression
61
Q

Morphine

Onset, Duration, half-life

A

Onset - IM 5-10 min, IV 2-5 min
Duration - 1-2 hours
Half-life - 2 hours

62
Q

Morphine

Dosages for significant pain

A
IM (ACP1, ACP2, CCP)
>70 years 2.5-5mg
Repeat at up to 5mg every 10 min
Max dose 10mg
70 years 2.5mg
Repeat at 2.5mg every 5 min
Max dose 10mg
63
Q

Morphine

Dosages for autonomic dysreflexia

A

.

64
Q

Naloxone

Indications

A

Respiratory depression secondary to administration of narcotic drugs

65
Q

Naloxone

Contraindications

A

KSAR or hypersensitivity

66
Q

Naloxone

Precautions

A

Pre-existing cardiac disease

67
Q

Aspirin Contraindications

A

KSAR
Chest pain associated with psychostimulant OD
Bleeding or clotting disorders (e.g. Haemophilia)
Current GI bleed or peptic ulcer
Patient

67
Q

Ondansetron Indications

A

Nausea and/or vomiting

Prophylactic for patient presenting with ACS

68
Q

Ondansetron contraindications

A

KSAR to ondansetron or other 5-HT3 receptor antagonists
Congenital long QT syndrome
Patient

69
Q

Ondansetron adult dosages

A

IM (ACP1, ACP2, CCP)
4-8 mg - total max 8mg
IV (ACP2, CCP)
4-8 mg - total max 8mg