Macrominerals Flashcards
Functions of calcium?
Provides rigidity and strength to bones and teeth Blood coagulation Muscle contraction Myocardial action Neuromuscular irritability
Form of calcium found in bones and teeth?
Hydrated tricalcium phosphate
Hydroxyapatite
Where Ca salts are deposited and resorbed?
Bone trabeculae
Required to form thrombin?
Calcium
Prothrombin
Thromboplastin
Sustained muscular contractions?
Tetany
Factors influencing Ca absorption? (5)
Needs of the body Gastric acidity Vitamin D Ca:P ratio Exercise
Storage of Ca and P?
Bone trabeculae
Regulates Ca balance and bone formation? (3)
Bone, kidney, intestine
PTH
Vitamin D
Maintains normal level of serum calcium?
PTH
Can rapidly lower a high serum calcium level?
Calcitonin
RDA of calcium?
800mg/day
RDA of calcium for infants?
360-540 mg
RDA of calcium from 1-10 yrs old?
800 mg
RDA of calcium for 11-18 yrs old?
1200 mg
Food with highest level of calcium?
Cheddar cheese
Best sources of calcium? (3)
Cheeses
Milk
Dark green leafy vegetables
Recommended for people who cannot eat dairy products? (2)
Calcium carbonate or
Oyster shell calcium
Conditions that can result in high levels of calcium? (3)
Idiopathic hypercalcemia
Hypercalcinuria
Hyperparathyroidism
Excess calcium in blood?
Idiopathic hypercalcemia
Excess calcium in urine?
Hypercalcinuria
Caused by prolonged and excessive intake of milk?
Milk-alkali syndrome
Ratio of Ca:P in bone?
2:1
True or false. The amount of P in the body is controlled by absorption rather than excretion in the urine?
False
Functions of phosphorus? (3)
Formation of bone and tooth
Production and transfer of phosphates
Regulates acid base balance
Any substance produced by physical and chemical changes within the organism?
Essential metabolite
Acts as buffers in blood and tissue?
Phosphates
RDA of phosphorus?
800-1200 mg
Foods rich in phosphorus? (5)
Meat Fish Poultry Eggs Milk
Chemical nature of bone?
60% inorganic material
25% collagen
15% water
5% cells
2 phases in bone growth?
1 formation of collagen
2 calcification
A process when amorphous calcium phosphate is deposited in the collagen fibrils?
Seeding or nucleation
Factors affecting the bone crystals. (3)
Organic matrix
Degree of phosphorylation
Amount of ground substance
A compound of P with 2 or more amino acid, which remains after enamel mineralization?
Phosphopeptides
Amino acid serine combined with phosphorus?
O-phosphoserine
Reduction of quantity of bone?
Osteoporosis
Atrophy of bone?
Osteoporosis
A condition in which rate of bone resorption is greater than the rate of bone formation?
Osteoporosis
Etiologic factors of osteoporosis? (5)
Age Endocrine abnormalities Hereditary disease Poor nutrition Hematologic disorders
A type of anticonvulsant which can cause osteoporosis?
Phenytoin
Due to disuse or immobilization of bone?
Localized osteoporosis
Commonly affected by osteoporosis?
Women over age 60
Low back pain?
Lumbago
True or false. In osteoporosis the pain is intermittent, while in osteomalacia it is continuous?
True
Reduced bone mass?
Osteopenia
Measures total body calcium?
Dual-photon absorptiometry
Measures mineral content in the skeleton?
Computed axial tomography
Treatment for osteoporosis? (6)
Ingestion of: high calcium diets, estrogen, fluoride, calcitonin, PTH, vitamin D
Incomplete development of enamel?
Enamel hypoplasia
An imperfection in enamel resulting from inadequate mineralization?
Hypocalcification
Hypoplasia is characterized by?
Pitting
Sign of hypocalcification?
Opaque, chalky white enamel
One major cation in animal tissue?
Magnesium
Central component of chlorophyll?
Magnesium
Functions of magnesium? (4)
Cellular respiration
Activator of coenzymes
Production of energy
Protein synthesis
Symptoms of Mg deficiency? (6)
Hyperexcitability Behavioral disturbances Weakness Depression Tremors Convulsions
RDA of Mg in male adult? For female?
Male: 350 mg
Female: 300 mg
Sources of Mg? (4)
Whole grains
Nuts
Soybeans
Green leafy vegetables