macrocytic anaemia Flashcards
1
Q
what are causes of megaloblastic anaemia?
A
vit b12 deficiency
folate deficiency
pernicious anaemia
2
Q
what is pernicious anaemia?
A
autoimmune atrophic gastritis leads to loss of parietal cells and intrinsic factor so can’t absorb b12
3
Q
what are causes of non megaloblastic?
A
pregnancy
alcohol excess
liver disease\hypothyroid
4
Q
what are neurological feeatures of b12 deficiency?
A
polyneuropathy of peripheral nerves
subacute combined spinal degeneration
5
Q
what are causes of b12 deficiency?
A
pernicious anaemia
poor diet
gastrectomy
ileal disease
