macrocytic anaemia Flashcards

1
Q

what are causes of megaloblastic anaemia?

A

vit b12 deficiency
folate deficiency
pernicious anaemia

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2
Q

what is pernicious anaemia?

A

autoimmune atrophic gastritis leads to loss of parietal cells and intrinsic factor so can’t absorb b12

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3
Q

what are causes of non megaloblastic?

A

pregnancy
alcohol excess
liver disease\hypothyroid

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4
Q

what are neurological feeatures of b12 deficiency?

A

polyneuropathy of peripheral nerves

subacute combined spinal degeneration

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5
Q

what are causes of b12 deficiency?

A

pernicious anaemia
poor diet
gastrectomy
ileal disease

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