M9 Systems Microbiology Flashcards

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1
Q

what is the lower respiratory tract

A

sterile

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2
Q

what is a sign of poor oral health

A

Bacteria constantly going into bloodstream,

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3
Q

what does the oral population influence

A

rest of resp system

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4
Q

where would you find Group A streptococci

A

at back of throat

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5
Q

what sort of environment is the Gastro Intestinal Tract in

A

an Anaerobic environment

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6
Q

Coliforms:

A

Gram (-ve) organisms of GI
- E. Coli (most important)!

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7
Q

Ingestion:

A

major source of colonisation

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8
Q

Shedding of mucosa -

A

communities built up if it does not get replaced

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9
Q

Bile salt:

A

interupt fat, damage membranes

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10
Q

Natural flora

A

bacteria already in stomach, symbiotic relationship

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11
Q

name the viral diseases of the GI tract

A
  • norovirus
  • rotavirus
  • cryptosporidium
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12
Q

Norovirus

A

(main GI infection)
aggressive, rapid transmition

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13
Q

Rotavirus

A

(acute inflammation of small intestine)

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14
Q

Multicellular disease of GI:

A

tape worm
Cryptosporidium: protozome

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15
Q
  • Prokaryotic infections of GI:
A

Endogenous or Exogenous (ingested bacteria)
- E. coli, Camplylobacter, C. diff

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16
Q

in E.coli variants what are variants tagged by

A

surface pill, fimbrie, flagella

17
Q

E. Coli 0157

A

toxin produced, damage to gut

18
Q

Clostridiodes difficile

A

(antibiotic associated diorhoea)
- Stop predisposing antibiotic treatment!
- poor bowel flora
- 1st line treatment is Vancomycin orally
-Gram -ve spectrum, not absorbed through gut

19
Q

Dysbiosis:

A

gut microbial factors

19
Q

Antibiotic therapy:

A

C.difficile proliferates in absence of normal flora

20
Q

disturbed gut microbiome =

A

weakened intestinal musodal barrier

21
Q

Importance of GI Microbiome

A

Gut linked to ageing, cancer, autism