m4 drills Flashcards
What happens when monoamine oxidase inhibitors are combined with tyramine rich food?
I. Accumulation of precursor amines
II. Increased in BP
III. Non-metabolism of Tyramine
Options: A. I and II, B. I and III, C. I, II, III, D. I only, E. III only
What type of interaction occurs when two drugs alter the absorption of one of the drugs?
A. Pharmacokinetic interaction
Options: A. Pharmacokinetic interaction, B. Pharmacodynamics interaction, C. Physico-chemical interaction, D. Pharmaceutical interaction, E. Chemical interaction
What should be monitored to assess the effectiveness of Naloxone administered to a patient?
I. Absence of fever
II. Respiratory rate has normalized
III. Seizure activity has stopped
IV. Chest pain has diminished
Options: A. I and II, B. II and III, C. II only, D. IV only, E. I, II, IV
What is TRUE about Bioavailability?
I. Rate and extent of drug distribution
II. Refers to the amount of drug in the bloodstream
III. Rate and extent of drug clearance
Options: A. I and II, B. II only, C. III only, D. I and III, E. II and III
Which statements are TRUE about Bioavailability?
I. Reflects the fraction of drugs metabolized
II. Always poor in orally administered drugs
III. Greatly affected by drug absorption
Options: A. I and II, B. II and III, C. I, II, III, D. II only, E. III only
Which statement is CORRECT regarding drug routes?
I. In IV route, drugs are not absorbed but have 100% bioavailability
II. In ORAL route, drugs are poorly absorbed but have 100% bioavailability
III. In Ly route, drugs have good absorption and have 100% bioavailability
Options: A. I and II, B. II and III, C. I, II, III, D. I only, E. III only
What factors will directly lead to a drug interaction?
I. Multiple pharmacologic effect of drugs
II. Pharmacokinetic variability of a patient
III. Pharmacoeconomics evaluation of drugs
Options: A. I and II, D. I only
