M3 C12 Communicable diseases Flashcards
what are the 4 different types of pathogens
- virus
- fungi
- bacteria
- protoctista
what is a pathogen
a disease causing organism
define communicable disease
a disease caused by pathogen that can be transmitted
what are the features of bacteria [5]
- prokaryotic
- reproduce rapidly
- damage cells
- can release toxins which are toxic to host
- can be killed w/ antibiotics
what are the defining features of fungi [5]
- eukaryotic
- most are multicellular (exp. yeast)
- digestion is extracellular
- SAPROPHYTIC (feed on dead tissue) or PARASITIC (living tissue… parasitic are pathogenic
- reproduce by producing spore
describe the features of viruses [5]
- non-living
- very small
- genetic material inserted into host cell, hijacks hosts’ biochemistry
- all natural viruses are pathogenic & can cause disease in any other type of organism incl. bacteria
- some viruses modified to treat disease by killing pathogen
describe the features of protoctistsa [5]
- eukaryotic
- varied, organisms which dont fit into other groups
- small number are pathogenic in plants and animals
- the protists causing disease are parasitic
- often need a vector to transfer from one individual to another
what are the two modes of action of a pathogen on a host
- DIRECT DAMAGE OF TISSUE, viruses & protists damage cells as they burst to release new pathogens, protists use cell contents during reproductions.
- PRODUCTION OF TOXINS, leading to damage of tissues (most bacteria & some fungi, the toxins are a by-product of their metabolism)
what is meant by the term transmission
- the way in a which a parasitic microorganism travels from one host to another
what are the 3 ways of direct transmission affecting animals
- direct contact: contagious diseases eg. Athletes foot. Kissing and exchange of bodily fluids eg. STD
- inoculation: Breaks in the skin/animal bite/puncture wound/ sharing needles
- ingestion: taking in contaminated food/drink
what are the 3 ways of indirect transmission
- fomites: inanimate objects
- droplet infections: droplets of saliva
- vectors: transmit pathogens from one host to another (water can be a vector, malaria via mosquito)
What are the factors affecting the transmission of pathogens which can lead to animal diseases?
- environmental: overcrowding/ living & working conditions
- poor nutrition
- compromised immune system
- poor disposal of waste, breeding site for vectors
describe macrophages
- larger cells
- longer lived
- made in bone marrow
- travel as monocytes until settled in tissues to become macrophages
- found in lymph nodes/ alveolar walls/liver
- often are APCs
What is meant by a passing defence
- Present before pathogen entry
- barriers to entry of pathogens
Describe the passive physical defences of a plant
LIGNIN- waterproof, almost completely indigestible
WAXY CUTICLE- prevent water collecting on cell surface
CELLULOSE CELL WALLS- physical barrier, contains variety of chemical defences which are activated in presence of pathogen
BARK- contains chemicals that work against pathogens
STOMATA-closure, stomata are possible entry points for
outline the active defences induced in a plant response to being invaded by a pathogen
- deposition of callose between plant cell wall & membrane, strengthens cell wall & blocks plasmodesmata
- bursts of highly reactive oxygen molecules capable of damaging pathogens
what are/what do cytokines do
- cell signalling molecules that inform other phagocytes that body is under attack
- stimulates others to move to site of infection
- can increase body temp. & stimulate specific immune responses
explain canker
a sunken necrotic lesion in the woody tissue such as the main stem or branch. It causes death of the cambium tissue in the park
what are the non-specific/ primary defences of animals
- SKIN, physical barrier which prevents entry of pathogen. cells of the epidermis dry out as they migrate to surface of the skin. Lower pH. makes a hostile place for bacteria
- LYSOZYMES, in tears & urine. kills pathogens & prevents infection
- EXPULSIVE REFLEXES, coughing/sneezing ejects pathogen from respiratory system. diarrhoea
- MUCUS MEMBRANES, line internal cavities exposed to the external air, contain goblet cells (produce mucus) and cilliated epithelial ( (waft mucus)
- lungs are warm and moist :. +hospitable for
pathogens - STOMACH ACID: kill pathogens, secreted by stomach lining cells
- EAR WAX: natural barrier to dirt & pathogens. prevent entry into inner ear
- FEMALE REPRODUCTIVE SYSTEM: cervix-mucus plug, barrier. vagina-relatively acidic environment
what is involved in the formation of a blood clot
- clotting factors
- platelets
- cell signalling molecules
how do wounds repair
- the clot dries out, forming a hard tough scab. keeping out pathogens.
- new epidermal cells grow underneath
- blood vessels regenerate
- collagen fibres are deposited to strengthen the new tissue
- scab
describe neutrophils
- common
- lobed nucleus
- released in large numbers
- large lysosomes
- dead neutrophils can collect and form pus
- short lived, die after ingesting bacteria
- frequently leave blood stream to patrol tissues for foreign bodies