M2.2

Question 1

L2:
STANDARD SOLN / UNKNOWN used

Answer 1

0.1N H2SO4 (SULFURIC ACID)

Question 2

L2:
base / known soln / primary standard used

Answer 2

Na2CO3 sodium carbonate

Question 3

L2:
indicator used

Answer 3

METHYL RED

Question 4

formula for AVERAGE NORMALITY

Answer 4

N1 + N2 + N3 / 3

Question 5

L3:
sample used in content uniformity test

Answer 5

SODIUM BICARBONATE tablets

Question 6

known conc. / standrad soln. used in assay of NaHCO3

Answer 6

0.1N H2SO4

Question 7

indicator in assay of NaHCO3

Answer 7

METHYL RED

Question 8

Assures that the STRENGTH of a therapeutic product REMAINS WITHIN SPECIFIED ACCEPTANCE LIMIT

Answer 8

CONTENT UNIFORMITY

Question 9

Used to establish within limits that a product has UNIFORM AMOUNTS OF AI in batch preparations of pharmaceutical dosage forms

Answer 9

CONTENT UNIFORMITY TEST

Question 10

2 USP SPECIFICATION FOR NaHCO3

Answer 10

1. INDIVIDUAL ASSAY
2. CONTENT UNIFORMITY BY BATCH

Question 11

(INDIV ASSAY)
USP SPECIFICATION OF NaHCO3

Answer 11

95% - 105%

Question 12

(CONTENT UNIFORMITY ASSAY)
USP SPECIFICATION OF NaHCO3

Answer 12

85% - 115% in each 10 dosage units

Question 13

formula for %A

Answer 13

mL x N x mEq wt / gsx x 100

Question 14

For the normality of standard sulfuric acid, use the calculated _______ in ALL trials.

Answer 14

AVERAGE NORMALITY

Question 15

In Assay, the amount/content of analyte in a sample is determined based on the ________ reacted with the analyte.

Answer 15

VOLUME OF STANDARD SOLN

Question 16

In Assay, the _______ in a sample is determined based on the volume of standard solution reacted with the analyte.

Answer 16

AMOUNT/CONTENT OF ANALYTE

Question 17

TRANSFER of a substance from one container or vessel to another such WITHOUT LOSING the content by;
– rinsing the original vessel, and
– adding the washings to the receiving vessel

Answer 17

QUANTITATIVE TRANSFER

Question 18

highly purified compound that serves a REFERENCE MATERIAL

Answer 18

PRIMARY STANDARD

Question 19

INDICATOR USED IN Standardization of 0.1 N Sodium hydroxide Solution

Answer 19

PHENOLPHTHALEIN

Question 20

what is the known soln. / base in the Standardization of 0.1 N NaOH

Answer 20

0.1N H2SO4

Question 21

In Standardization of 0.1 N NaOH, Sulfuric acid solution is considered a

Answer 21

SECONDARY STANDARD

Question 22

a substance whose content/purity/concentration has been found by COMPARISON AGAINST A PRIMARY STANDARD.

Answer 22

SECONDARY STANDARD

Question 23

A highly pure substance

Answer 23

PRIMARY STANDARD

Question 24

Usually, a solution with KNOWN CONCENTRATION

Answer 24

SECONDARY STANDARD

Question 25

Standard Solution (liquid)

Answer 25

SECONDARY STANDARD

Question 26

Dried solid

Answer 26

PRIMARY STANDARD