M2 endo physio Flashcards

1
Q

GLUT 1

A

Insulin independent

RBCs, brain, immune cells

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2
Q

GLUT 2

A

Insulin independent

Pancreatic beta cells, kidney, liver, intestinal cells

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3
Q

GLUT 3

A

Insulin independent

brain, placenta

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4
Q

GLUT 4

A

Insulin DEPENDENT

Skeletal muscle, cardiac muscle, adipocytes

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5
Q

Factors that increase insulin release

A
glucose
ACh
CCK
Glucagon
GLP-1
Amino Acids
Ketoacids
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6
Q

Factors that decrease insulin release

A

Epi
Norepi
Somatostatin (GH)

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7
Q

Types of deiodinase

A

Type 1 (D1): makes peripheral T3 (active) and rT3 (inactive)

Type 2 (D2): peripheral and intracellular T3 (activates); removes outer ring iodine

Type 3 (D3): peripheral thyroid hormone inactivation; removes inner ring iodine

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8
Q

Growth factor hormone receptors

A

insulin, IGF-1, PRL, GH

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9
Q

G protein coupled receptor

A

Ne, E, PTH, glucagon, hypothalamic and pituitary hormones

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10
Q

Nuclear hormone receptor

A

steroid, retinoic acid, thyroid

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