M19 Flashcards
It is characterized by a combination of rigidity, bradykinesia, tremor and postural instability
Parkinsonism
An alternative but complementary approach has been to restore the normal balance of cholinergic and dopaminergic influence on the basal ganglia by the use of
Antimuscarinics
Parkinson’s is due to loss of what neurotransmitter
Dopamine
What are the 5 types of drugs used in parkinsonism
Dopamine precursor, dopamine agonists , MAO inhibitors, COMPT inhibitors, and muscarinic antagonists
Drug under dopamine precursor
Levodopa
A dopamine agonists are used as sole agents in early Pharkinson’s disease and adjunct to L-dopa
Pramipexole and ropinirole
D3 agonist
Pramipexole
Primary drug used in Parkinson’s disease
Levodopa
Drugs under muscarinic antagonists
Benztropine
Improve tremor and rigidity not bradykinesia
Benztropine