M1 Lec 1 Flashcards
What was the first reference to the brain in human records?
Edwin Smith Papyrus
what is trepanation?
ancient neurosurgery
luigi galvani
discovered animal electricity
* precursors to nerve impulses and muscle contraction
franz gall
localization of brain function - associated mental functions w distinct neural regions
phrenology
camillo golgi
* what is golgi stain
* what is reticular theory
innovato of neural staining
* golgi stain: silver chromate stain of individual stain
* reticular theory: brain and nervous system are a single network of fibers
santiago ramon y cajal
* neuron doctrine:
refined golgi staining
* neuron doctrine: nervous system is made of discrete individual cells
hodgkin and huxley
ionic mechanisms of action potential
charles sherrington
synaptic transmission
otto loewi
neurotransmitters/chemical signaling
two major cell types
neurons and glial cells (support cells)
neuronal structure
cell body
(soma) contains the nucleus and other organelles
neuronal structure
dendrites
recieve signals from other neurons
neuronal structure
axon
transmits signals to other neurons or target cells
neuronal structure
axon hillock
where the action potential is initiated
neuronal structure
myelin sheath
* formed by?
insulating layer around the axon
* formed by schwann cels or oligodendrocytes
neuronal structure
nodes of ranvier
gaps in the myelin sheath
neuronal structure
axon terminal
releases neurotransmitters
neuronal structure
synapse
the junction between two neurons
synapse:
* presynaptic:
* postynaptic:
- presynaptic: axon
- postynaptic: dendrite