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INTERNAL MEDICINE > M1: Fever & Hyperthermia > Flashcards

M1: Fever & Hyperthermia Flashcards

0
Q

If it exceeds the set point of our thermostat

A

Hot sensation

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1
Q

Acts as body’s thermostat

A

Hypothalamus

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2
Q

Release of heat by water vapor

A

Exhalation

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3
Q

More effective in releasing heat

A

Evaporation

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4
Q

Temperature lower than the thermostat

A

Cold

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5
Q

Heat production by

A

Shivering

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6
Q

Increases metabolism to release

A

Hea

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7
Q

Heat production

A

Hot

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8
Q

Heat preservation

A

Cold

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9
Q

Elevated body temperature and increase in hypothalamic set point.

A

Fever

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10
Q

Hyperpyrexia

A

> 41.5°C

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11
Q

Substance that causes fever

A

Pyrogen

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12
Q

Direct effect to the hypothalamus

A

Exogenous pyrogens

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13
Q

Needs to be stimulated first. Indirect effect to the hypothalamus.

A

Endogenous pyrogen

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14
Q

Uncontrolled increase in body’s temperature that exceeds body’s ability to lose heat. May lead to heat stroke.

A

Hyperthermia

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15
Q

Heat stroke usually occurs due to

A

Exogenous exposure (environment)

16
Q

Exertional: exercise in higher than normal heat and humidity. Nonexertional: drugs. Examples are anticholinergics.

A

Heat stroke

17
Q

Induced by amphetamins, cocaine, mdma, demethylamide & etc.

A

Drug Induced Hyperthermia

18
Q

Inhalational anestheics & succinylcholine

A

Malignant Hyperthermia

19
Q

Manifestation of heat stroke/hyperthermia

A

Warm dry skin

20
Q

Increased hypothalamic set point

A

Fever

21
Q

Exogenous heat exposure or endogenous heat production

A

Hyperthermia

22
Q

Treatment for fever

A

Antipyretics & Anti-cytokine therapy

23
Q

Examples of Antipyretics

A

NSAIDs, Aspirin & Paracetamol “NAP”

24
Q

Specific to act on the hypothalamus thus decreasing PGE2

A

Paracetamol

25
Q

Internal cooling for Hyperthermia

A

Gastric lavage, peritoneal lavage & cooling the blood

26
Q

External cooling for Hyperthermia

A

Cooling blankets, fans and ice baths

INTERNAL MEDICINE (2 decks)

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