M1 Flashcards

1
Q

define selective breeding

A

artificial selection and breading of natural genetic variants found in the wild

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2
Q

what was believed about preformation before the 1600s

A

the sperm contains a miniature adult

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3
Q

4 objectives of cell theory

A

smallest unit of life
pre existing cells
all organisms made of cells

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4
Q

who is responsible for the discovery of cell theory

Gregor Mendel, 1866
Matthias Jakob Schleiden and Theodor Schwann, 1838
Charles Darwin, 1859
Walter Sutton and Theodor Boveri,1902

A

Matthias Jakob Schleiden and Theodor Schwann, 1838

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5
Q

What did Charles Darwin theorize about

A

evolution through natural selection

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6
Q

Which scientist was repsonsible for disocvering traits are passed on generation to generation through peas?

Gregor Mendel, 1866
Matthias Jakob Schleiden and Theodor Schwann, 1838
Charles Darwin, 1859
Walter Sutton and Theodor Boveri,1902

A

Gregor Mendel, 1866

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7
Q

which word is associated with this definition:
Chromosomes carry the genetic information

a) selective breeding
b) hereditary transference
c) chromosomal theory of inheritance

A

c) chromosomal theory of inheritance

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8
Q

Sutton generated 5 conclusion of chromosomal theory of inheritance which two were wrong

A

the first division of meiosis is equational
the second division of meiosis is reductional

(it was the opposite)

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9
Q

Name Suttons 5 conclusions

A
  1. Two sets of chromosomes (paternal and maternal).
  2. Synapsis (i.e., pairing of chromosomes during meiosis) is the pairing of the homologous chromosomes.
  3. The first division of meiosis is equational!!! (turned out wrong)
  4. The second division of meiosis is reductional!!! (turned out wrong)
  5. Chromosomes retain a morphological individuality throughout the various cell-divisions
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10
Q

What is the functional determinant of biochemical properties of cells

mRNA
tRNA
cDNA
DNA

A

DNA

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11
Q

Who discovered structure of DNA

A

Watson, crick, franklin

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12
Q

define genome

A

all genetic information that determines an organism’s hereditable traits
nuclear DNA + mitochondrial DNA

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13
Q

what does a nucleotide NOT include
5-carbons sugar
nitrogenous base
chromatin
phosphate groups

A

chromatin

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14
Q

How many hydrogens bonds for C and G

A

3

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15
Q

How many hydrogen bonds for A and T

A

2

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16
Q

What determines the sequence of amino acids in a gene?

A

The sequence of nucleotide on the coding strand

The coding strand is also known as the sense strand or positive-sense strand.

17
Q

What is another name for the coding strand?

A

Sense strand, positive-sense strand, positive (+) strand

The coding strand is crucial for determining the amino acid sequence.

18
Q

what arm does cricks strand start from the 3’ direction on a chromosome

short arm (p-arm)
long arm (q-arm)

19
Q

Coding sequences of genes must be on the Watson strand.

True or False

20
Q

Which is written on top Watson or cricks

A

Watson strand

21
Q

define chromatin

A

complex of DNA, RNA, histone, and nonhistone protein that make up uncoiled chromosome

22
Q

What percent of chromatin is euchromatin of an interphase chromatin

23
Q

What percent of chromatin is heterochromatin of an interphase chromatin

24
Q

define centromere

A

specialized heterochromatic region where sister chromatid remain attached after replication

25
Q

Where do spindle fibers attach to
exactly in the middle
centrosome
centromere
telomere

A

centromere

26
Q

two chromatids are attached at the centromere by what protein complex

HBA1
cytokines
centromere complex
cohesins

27
Q

describe what numbers and letters mean when describing loci on a gene (ex. 16p13.3)

A

chromosome
arm
region
band
sub-band

28
Q

How many genes are there in mitochondrial gene

29
Q

what is word that describes two homologous chromosomes associating with each other during meiosis

30
Q

define diploid

A

2 set of chromosome, 1 inherited from each parent

31
Q

define haploid

A

1 set of chromosome

32
Q

define polyploid and name an example of

A

a cell containing more than one pair of homologous chromosomes

33
Q

what differentiated humans and gorillas

A

the fusing of two ancestral chromosome which created chromosome 2