M02 Flashcards
Define hematopoiesis
formation of all blood cells (RBCs, WBCs, & platelets)
Define a “formed element” and know the three formed elements by their common names and more scientific names
solid portion made up of
- RBCs (erythrocytes)
- WBCs (leukocytes)
- platelets (thrombocytes)
Know the location where all blood cells originate and that they originate from a hematopoietic stem cell. More specifically, know which cells originate from myeloid stem cells, and which originate from lymphoid stem cells.
Know the scientific name of red blood cells, describe their shape, and describe characteristics
- also called erythrocytes
- biconcave disc shape: so they can easily
transport gases & squeeze through capillaries - lack mitochondria & nuclei
- avg lifespan is 120 days
Explain the function of hemoglobin inside of red blood cells
- transports oxygen & some carbon dioxide through the blood
Oxyhemoglobin (with O2) is bright red.
Deoxyhemoglobin (without O2) is dark red.
Name the hormone and conditions that triggers the release of new red blood cells
Hemoglobin
What is the average life span of a red blood cell?
120 days
What nutrients are required for erythropoiesis?
- vitamin B
- folic acid
- iron
Define anemia
- condition in which the O2 carrying capacity of blood is reduced due to the deficiency of RBCs or hemoglobin
Name the two categories of white blood cells. Name the types of WBCs within each category
Granulocytes: granular cytoplasm & short life span
- neutrophils
- eosinophils
- basophils
Agranulocytes: without distinctly staining granules
- lymphocytes
- monocytes
Define diapedesis
WBCs can squeeze between cells of a capillary wall & leave blood vessel, then migrate toward infection site so that they can fight pathogens
Define chemotaxis
attraction of WBCs to an infection site by chemicals released by damaged cells
Define phagocytosis
englufing & digestion of pathogens
Be able to describe the appearance of each white blood cell or identify it based on its description. For example, a neutrophil has small, light purple granules and a lobed nucleus. Descriptions in your PowerPoint will help with this
Identify the main functions of each type of white blood cell
Identify the functions of Neutrophils
Identify the functions of Eosinophils
Identify the functions of Basophils
Identify the functions of Monocytes
Identify the functions of Lymphocytes