Lytics Flashcards
1
Q
Tenectaplase (TNK)
A
Non-antigenic
Fibrin specific
Single dose
2
Q
Reteplase
A
limited fibrin specificity
2 boluses - needs weight adjustment
3
Q
TPA (alteplace)
A
moderate fibrin specificity
bolus + administered as drip
4
Q
Streptokinase
A
HIGHLY ANTIGENIC
NO fibrin specificity
can only use once
5
Q
use of lytics
A
Sx onset within 12 hours STEMI only
DO NOT USE IN NSTEMI
>120min away from PCI capable center
-transfer to PCI facility after lytic use!
perform angio within 24 hours (not first 2-3 - inc’d bleeding risk)
6
Q
TNK
A
full dose TNK, ASA, plavix, UFH (if Cr abn)