Lymphomas & Plasma Cell Disorders

Question 1

MM Lab findings include what type of cells?

Answer 1

-Mott
aka morula
aka Russell bodies
literally look like grapes within plasma cells

Question 2

What are Russell bodies made up of?

Answer 2

immunoglobulin accumulation , representing accumulation of excess mucopolysaccharides and globulins within the endoplasmic reticulum

Question 3

what condition is associated with epstein barr virus?

Answer 3

Burkitt’s lymphoma

usually associated with IM, can also cause human cancer. the virus combines with acquired genetic mutations to produce disease.

Question 4

Prominent vacuolation involving the cytoplasm of abnormal lymphoblast-like cells seen in the peritoneal body fluid preparation shown is a distinctive feature of which disease?

Answer 4

Burkitt Lymphoma

• prominent cytoplasmic vacuolation of Burkitt lymphoma cells help ID cells.