Lymphoid Tissue 2 Flashcards

1
Q

What is the largest lymphatic organ?

A

spleen

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2
Q

What is the blood supply of the spleen?

A

splenic artery and vein

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3
Q

What does the splenic artery supply?

A

spleen, parts of stomach, and pancreas

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4
Q

What two veins connect to form the portal vein?

A

splenic and superior mesenteric vein

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5
Q

What are functions of spleen?

A

-b and t cell replication
-remove particulate matter and remove old or defective RBC
-recycle iron from HB
-hematopoiesis in fetus

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6
Q

If spleen is removed, what takes over the functions?

A

liver and bone marrow

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7
Q

What allows for arteries and veins to get into the spleen?

A

trabeculae

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8
Q

What is white pulp of spleen?

A

collection of B and T cells

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9
Q

What is the red pulp of the spleen?

A

filled with blood

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10
Q

What are sinusoids of spleen?

A

contain mostly blood

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11
Q

What are pulp cords of spleen?

A

cellular components that contain large numbers marcophages and neutrophils
-large numbers of reticular cells and fibers

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12
Q

What is at the center of white pulp of spleen/

A

central artery
-may or may not have germinal center

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13
Q

What is the marginal zone of spleen?

A

lighter staining portion of the exterior of white pulp

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14
Q

What is the function of white pulp?

A

site of antigen presentation
-phagocytosis, macrophages, plasma cells, and helper t cells

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15
Q

What are splenic nodules?

A

enlarged germinal centers visible with naked eye

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16
Q

What are PALS?

A

periarteriolar lymphatic sheaths
-right around the central artery of the white pulp
-T cells

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17
Q

What are central arteries branches of?

A

the trabecular arteries

18
Q

What do central arteries branch into?

A

penicillar arterioles

19
Q

What do penicillar arterioles terminate into?

A

sheathed capillaries

20
Q

What is open circulation of spleen?

A

when the penicillar arterioles dump blood right into the splenic cords

21
Q

What is closed circulation of the spleen?

A

penicillar arterioles dump blood into the sinusoids

22
Q

What are sheathed capillaries?

A

capillaries that do not have endothelial cells
-have macrophages that look at the blood

23
Q

What makes up a majority of the spleen?

A

red pulp
75%

24
Q

What are stave cells?

A

elongated, fusiform endothelial cells that are along the splenic sinusoids
-do not have intercellular junctions

25
Q

What is the purpose of the sinuoids?

A

allow red blood cells to leave

26
Q

What helps to ID and destroy old RBC?

A

the fact that they are not able to leave out of the stave cells
-tells the macrophages that it is time to be destroyed

27
Q

What does MALT stand for?

A

muscosa-associated lymphoid tissue

28
Q

Where is MALT located?

A

in gut tube, respiratory system, genitals, and urinary system

29
Q

What is the function of MALT?

A

detect antigens and initiate response

30
Q

What are tonsils?

A

epithelia lined collections of lymphoid nodules located in the oral and nasal cavities that provide immune surveillance of antigens entering the body through the mouth and nose

31
Q

Where are pharyngeal tonsils? (adenoids)

A

on the back of nasopharynx

32
Q

Where are palatine tonsils?

A

back of oral cavity (this is what gets removed when you think of them getting removed)
-between palatoglossal and palatopharyngeal arches
(anterior and posterior tonsilar pillars)

33
Q

Where are lingual tonsils?

A

at the posterior 1/3 of tongue

34
Q

What type of cells make up the palatine tonsils?

A

non-keratinized stratified squamous epithelium

35
Q

Which surface of palatine tonsil does not have a capsule?

A

the surface that faces into oral cavity

36
Q

What is the capsule that runs on the posterior of the palatine tonsil?

A

hemicapsule

37
Q

What are tonsillar crypts?

A

spaces in palatine tonsils that allow the food being eaten to go in and be surveyed to make sure there is nothing pathogenic in it

38
Q

What are dome areas of MALT?

A

connective tissue that projects into the lumen of thegut
-secrete IgA

39
Q

What are M-cells?

A

have lots of microfolds that allow for increased surface area to make sure there is nothing bad in it

40
Q

What is the appendix?

A

thing that sticks off cecum and contains a lot of lymphocytes (mostly B cells)
-herbivores use it to ferment bacteria