Lymphoid Tissue 2

Question 1

What is the largest lymphatic organ?

Answer 1

spleen

Question 2

What is the blood supply of the spleen?

Answer 2

splenic artery and vein

Question 3

What does the splenic artery supply?

Answer 3

spleen, parts of stomach, and pancreas

Question 4

What two veins connect to form the portal vein?

Answer 4

splenic and superior mesenteric vein

Question 5

What are functions of spleen?

Answer 5

-b and t cell replication
-remove particulate matter and remove old or defective RBC
-recycle iron from HB
-hematopoiesis in fetus

Question 6

If spleen is removed, what takes over the functions?

Answer 6

liver and bone marrow

Question 7

What allows for arteries and veins to get into the spleen?

Answer 7

trabeculae

Question 8

What is white pulp of spleen?

Answer 8

collection of B and T cells

Question 9

What is the red pulp of the spleen?

Answer 9

filled with blood

Question 10

What are sinusoids of spleen?

Answer 10

contain mostly blood

Question 11

What are pulp cords of spleen?

Answer 11

cellular components that contain large numbers marcophages and neutrophils
-large numbers of reticular cells and fibers

Question 12

What is at the center of white pulp of spleen/

Answer 12

central artery
-may or may not have germinal center

Question 13

What is the marginal zone of spleen?

Answer 13

lighter staining portion of the exterior of white pulp

Question 14

What is the function of white pulp?

Answer 14

site of antigen presentation
-phagocytosis, macrophages, plasma cells, and helper t cells

Question 15

What are splenic nodules?

Answer 15

enlarged germinal centers visible with naked eye

Question 16

What are PALS?

Answer 16

periarteriolar lymphatic sheaths
-right around the central artery of the white pulp
-T cells

Question 17

What are central arteries branches of?

Answer 17

the trabecular arteries

Question 18

What do central arteries branch into?

Answer 18

penicillar arterioles

Question 19

What do penicillar arterioles terminate into?

Answer 19

sheathed capillaries

Question 20

What is open circulation of spleen?

Answer 20

when the penicillar arterioles dump blood right into the splenic cords

Question 21

What is closed circulation of the spleen?

Answer 21

penicillar arterioles dump blood into the sinusoids

Question 22

What are sheathed capillaries?

Answer 22

capillaries that do not have endothelial cells
-have macrophages that look at the blood

Question 23

What makes up a majority of the spleen?

Answer 23

red pulp
75%

Question 24

What are stave cells?

Answer 24

elongated, fusiform endothelial cells that are along the splenic sinusoids
-do not have intercellular junctions

Question 25

What is the purpose of the sinuoids?

Answer 25

allow red blood cells to leave

Question 26

What helps to ID and destroy old RBC?

Answer 26

the fact that they are not able to leave out of the stave cells -tells the macrophages that it is time to be destroyed

Question 27

What does MALT stand for?

Answer 27

muscosa-associated lymphoid tissue

Question 28

Where is MALT located?

Answer 28

in gut tube, respiratory system, genitals, and urinary system

Question 29

What is the function of MALT?

Answer 29

detect antigens and initiate response

Question 30

What are tonsils?

Answer 30

epithelia lined collections of lymphoid nodules located in the oral and nasal cavities that provide immune surveillance of antigens entering the body through the mouth and nose

Question 31

Where are pharyngeal tonsils? (adenoids)

Answer 31

on the back of nasopharynx

Question 32

Where are palatine tonsils?

Answer 32

back of oral cavity (this is what gets removed when you think of them getting removed) -between palatoglossal and palatopharyngeal arches (anterior and posterior tonsilar pillars)

Question 33

Where are lingual tonsils?

Answer 33

at the posterior 1/3 of tongue

Question 34

What type of cells make up the palatine tonsils?

Answer 34

non-keratinized stratified squamous epithelium

Question 35

Which surface of palatine tonsil does not have a capsule?

Answer 35

the surface that faces into oral cavity

Question 36

What is the capsule that runs on the posterior of the palatine tonsil?

Answer 36

hemicapsule

Question 37

What are tonsillar crypts?

Answer 37

spaces in palatine tonsils that allow the food being eaten to go in and be surveyed to make sure there is nothing pathogenic in it

Question 38

What are dome areas of MALT?

Answer 38

connective tissue that projects into the lumen of thegut -secrete IgA

Question 39

What are M-cells?

Answer 39

have lots of microfolds that allow for increased surface area to make sure there is nothing bad in it

Question 40

What is the appendix?

Answer 40

thing that sticks off cecum and contains a lot of lymphocytes (mostly B cells) -herbivores use it to ferment bacteria