Lymphoid Organs. Flashcards

1
Q

What occurs in the lymphoid organs?

A

Antigens are presented to different immune components.

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2
Q

Do the lymphoid organs help to regulate immune responses?

A

Yes.

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3
Q

Lymphoid organs provide an environment for what?

A

Interactions between lymphocytes, APC’s and antigens.

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4
Q

Where in the developing embryo do lymphocytes come from?

A

The embryonic yolk sac.

The foetal liver.

The bone marrow.

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5
Q

Where are lymphocytes made in adult organisms?

A

The bone marrow.

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6
Q

Where in the adult body does lymphocyte differentiation occur?

A

The bone marrow.

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7
Q

Where are the 4 areas of the body that lymphocytes will develop in?

A

The thymus.

The bursa (only found in avians).

Peyers patches (in mammals).

The bone marrow.

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8
Q

What happens after lymphocytes have developed?

A

They travel to various parts of the body where they can respond to antigens.

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9
Q

What are the 4 locations of the body where mature lymphocytes will be found?

A

The tonsils.

The spleen.

The lymph nodes.

The peyers patches.

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10
Q

What name is given to the organs where lympoid development occurs?

A

Primary lymphoid organs.

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11
Q

What are secondary lymphoid organs?

A

The locations where lymphocytes carry out their function.

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12
Q

What 2 things happen to T cells in the primary lymphoid organs?

A

They are educated not to attack the bodies own cells.

They acquire their different antigen binding receptors (TCRs).

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13
Q

What does the education of lymphocytes mainly involve?

A

Killing any lymphocytes that recognise self antigens.

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14
Q

Lymphocytes should always kill what kind of antigens?

A

Foreign antigens.

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15
Q

Do lymphocytes encounter foreign antigens in the primary lymphoid tissues?

A

No, the only encounter foreign antigens in the secondary tissues.

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16
Q

What are the 2 classifications of secondary lymphoid tissue?

A

BALT = bronchial associated lymphoid tissue.

GALT = gut associated lymphoid tissue.

17
Q

What occurs in the secondary lymph tissues?

A

B and T cells are educated to recognise foreign antigens.

18
Q

What happens when lymphocytes encounter a foreign antigen?

A

They undergo differentiation and become an effector cell.

19
Q

What are effector B cells known as?

A

As plasma cells.

20
Q

What are the 2 types of effector T cells?

A

T helper cells (CD-4+).

Cytotoxic T cells (CD-8+).

21
Q

When will T cells acquire their TCR’s?

A

When they leave the primary lymph tissue.

22
Q

When can T cells perform their effector functions?

A

When they have been educated.

23
Q

What is the function of CD-4 T cells?

A

To present antigens to B cells.

24
Q

What is the function of CD-8+ T cells?

A

To kill infected cells and tumour cells.