Lymphoid Organs

Question 1

Central (primary) lymphoid organs

Answer 1

Bone marrow, thymus

Question 2

Peripheral (secondary) lymphoid organs

Answer 2

lymph nodes, spleen, tonsils, Peyer’s patches

Question 3

Extralymphoid tissues & organs:

Answer 3

gi., resp., urinary, repro., tracts, skin, blood & lymph, and wandering lymphocytes

Question 4

Lymphocyte recirculation is carried out by;

Answer 4

The circulatory system (blood). Permits continuous immune surveillance and ensures rapid response to antigens

Question 5

Pale staining cytoplasm with numerous processes, diffuse nucleus with prominent nucleolus. (hint: most originate from mesenchyme)

Answer 5

Reticular cell

Question 6

These types of cell predominate in loose lymphoid tissue

Answer 6

Reticular cells (fixed cells)

Question 7

These types of cell predominate in dense lymphoid tissue

Answer 7

Lymphocytes (free cells)

Question 8

A lymphoid nodule that has not seen antigen and is not stimulated is called

Answer 8

A primary (lymphoid) nodule. Lymphoid nodules are not limited to lymphoid organs.

Question 9

If the nodule is stimulated by antigenic stimulation it gets larger in size and develops a pale staining germinal center. What is this type of nodule now called

Answer 9

A secondary lymphatic nodule

Question 10

The germinal center contains numerous

Answer 10

Activated B lymphocytes

Question 11

The three types of lymphoid tissue are

Answer 11

Dense, loose, and nodular

Question 12

In nodular lymphoid tissue the predominant cell type is

Answer 12

lymphocytes

Question 13

In a germinal center the dark zone contains:

Answer 13

dividing B lymphocytes

Question 14

In a germinal center the light zone contains:

Answer 14

Non-dividing B lymphocytes and helper T cells.

Question 15

In a germinal center the functional correlation of the dark zone:

Answer 15

the proliferation of activated B lymphocytes (clonal expansion)

Question 16

In a germinal center the functional correlation of the light zone:

Answer 16

Selection of B lymphocytes, apoptosis of B cells that cannot discriminate between self and non-self antigens, surviving B lymphocytes begin differentiation into plasma cells and memory B cells

Question 17

In a germinal center the mantle zone contains:

Answer 17

young plasma cells and memory B cells

Question 18

In a germinal center the mantle zone functional correlation is:

Answer 18

temporary storage of young plasma cells and memory B cells

Question 19

Germinal centers appear after ____ and involute after about ____

Answer 19

primary antigenic response; 4 weeks

Question 20

The concave surface of a lymph node contains the _____

Answer 20

Hilus

Question 21

______ enter and leave at the hilus ______ leave at the hilus

Answer 21

Blood vessels; efferent lymphatics

Question 22

Left off on slide 18

Answer 22

need to make more cards