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MOHD3 Exam 2 > Lymphoid Disorders > Flashcards

Lymphoid Disorders Flashcards

1
Q

CD20

A

Mature B cells

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2
Q

CD10

A

Precursor B ells, germinal center cells

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3
Q

CD3

A

Pan-T cell markers

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4
Q

CD34

A

Myeloid and lymphoid precursors

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5
Q

White pulp enlargement of spleen caused by:

A

B cell lymphomas

Lymphoid hyperplasia

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6
Q

Red pulp enlargement of spleen caused by:

A

Congestion
Leukemia
Autoimmune processes

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7
Q

Benign reactive processes of unknown etiology

A

Lymphadenopathies

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8
Q

Immunophenotype of reactive lymphoid hyperplasia

A

CD20+, CD10+, bcl 6+, **bcl-2- in germinal centers

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9
Q

Most common cause of lymph enlargement in adults

A

Neoplasia

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10
Q

Lymphoid neoplasias common in children and young adults

A

Hodgkins Lymphoma

Burkitt Lymphomas

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11
Q

Most common lymphomas (2)

A

Diffuse large B cell lymphoma

Follicular lymphoma

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12
Q

Follicular lymphoma Immunophenotype

A

CD20+, **Bcl 2+, **CD10+, CD3-

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13
Q

Follicular lymphoma cytogentics

A

Bcl 2 gene rearrangement: t(14;18)

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14
Q

Most common type of lymphoma

A

Diffuse large B cell lymphoma

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15
Q

Immunophenotype of Burkitt lymphoma

A

CD19+, CD20+, *CD10+, Bcl 6+, Bcl-2-

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16
Q

Cytogenetics of Burkitt Lymphoma

A

t(8;14)

17
Q

Immunophenotype for Mantle Cell Lymphoma

A

CD19+, CD20+, CD5+, cyclin D1+

Bcl-6-, *CD10-, CD23-

18
Q

Cytogenetics of Mantel Cell Lymphoma

A

t(11;14)

19
Q

Associated w/ helicobacter pylori

A

Marginal zone lymphoma

20
Q

Immunophenotype of Hodgkin Lymphoma

A

CD30+, CD15+, CD45-

21
Q

Chronic Lymphocytic leukemia/small lymphocytic lymphoma immunophenotype

A

CD19+, CD20+, CD5+, Cd23+

22
Q

Low grade B cell lymphomas (4)

A

Follicular
Marginal zone
Mantle
Small Lymphocytic

23
Q

CD5+, CD20+, CD23+, CD10-

A

CLL/SLL

24
Q

CD10+ CD20+, CD5-, CD23-

A

Follicular Lymphoma

25
Q

CD5+, CD20+, CD10-, CD23-

A

Mantle Cell Lymphoma

26
Q

CD10+, CD20+, CD5-, CD23-

A

Burkitt

27
Q

CD20+, Cd5-, CD10-, CD23-

A

Mantle Zone Lymphoma

28
Q

CD19

A

precursor B cells, mature B cells

MOHD3 Exam 2 (13 decks)

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