Lymphedema and compression Flashcards
Main functions of lymphatic system:
regulate fluid balance
assist with infection control
How much fluid is removed from interstitial space/day?
18 liters
Where is fluid removal from?
80-90% through veins
remaining 2-4 liters thru lymph system
Estimates of lymphedema type:
23–45% of patients after breast cancer
21% of patients after ovarian cancer
28% of patients after endometrial cancer
Up to 70% of patients after prostate cancer
When does lymphedema occur?
when the lymphatics cannot remove the remaining interstitial fluid
Chief complaints of lymphedema?
Limb heaviness, paresthesias, achiness, skin tightness, poor-fitting clothes, altered cosmesis, decreased ADLs and ROM
Lymphatic anatomy:
superficial
deep
perforating
Superficial lymphatics
Drains the skin and subcutaneous tissue
Roughly parallels the veins
Deep lymphatics
Drains all else (deep tissues and organs)
Lymph
fluid made up of water, protein, dead/dying cells/cellular components, fatty acids, foreign material and debris
Lymphangion
functional unit of the lymph system
Smaller lymph anatomy:
capillaries precollectors collectors nodes trunks
Central Lymphatic Flow
Unidirectional valves Skeletal muscle contraction Respiratory pump Aortic pulsations Lymphangiomotoricity
What is fluid movement between capillaries, interstitium, and lymphatic system governed by?
hydrostatic and osmotic pressure
Dynamic insufficiency:
If the lymphatic load exceeds the transport capacity of the lymphatic system, edema will occur
Mechanical insufficiency:
a decrease in the maximal transport capacity of the lymphatic system, mechanical insufficiency can result
Types of lymphedema
primary
secondary
vessel abnormality
age on onset
Primary
10% of all cases
Congenital malformation or impairment of lymphatics
LE affected most often
Secondary:
Acquired
Disruption of or damage to lymphatics
Much more common
What illnesses is secondary lymphedema common in?
Filariasis (parasitic infection)
Cancer treatment
Chronic venous insufficiency
Vessel Abnormality
Aplasia
Hypoplasia
Hyperplasia
Lymph node fibrosis
Age at Onset
Congenital
Praecox
Tarda
Lipedema
Bilateral, symmetrical increase in adipose tissue deposition
What areas does lipedema most commonly affect?
Affects abdomen, buttocks, lower extremities but spares the feet
Causes of lipolymphedema;
Increased compliance of fat allows interstitial fluid to accumulate
Risk Factors for Lymphedema
Lymph node status Radiation therapy Time since surgery Air travel without compression Inflammation/Increased Lymphatic Load Decreased Lymphatic Return
Lymph Node Status
Surgical removal increases risk
More removed, the greater the risk
Sentinel lymph node
the first lymph node to receive lymph from a tumor
Radiation Therapy
Peri-lymphatic and lymph node fibrosis Skin damage Sclerosis/fibrosis Dermal atrophy Decreased sweat glands
What percentage of breast cancer patients who had lumpectomy and axillary radiation developed lymphedema?
26%
Time Since Surgery
Risk increases over time
Possibly due to lymphatic fatigue
Increased Body Mass Index
Air Travel Without Compression
Decreased atmospheric pressure on body while flying allows body to swell
May extrapolate to increased risk when going to areas of high elevation
Compression garment offsets this pressure change
Inflammation/Increased Lymphatic Load
Inflammation and infection increase lymphatic load
Avoiding strenuous activity of at-risk limb may prevent muscle microtrauma and inflammation – increased fluid that the patient’s lymph system may not be able to accommodate
Decreased Lymphatic Return
Constrictive clothing/jewelry
Tourniquets, blood pressure cuffs
Those Prone to Scar Tissue Formation
Trauma from surgical removal of tumor, nodes, and tissue dissection may cause more scar tissue formation in some patients, such as those at risk for keloids
PT Tests and Measures
for Lymphedema
Circumferential Measurements
Weight change with compression
Circulation
Sensory Integrity
Gold standard for lymphedema measurements?
volumetric displacement
Why is volumetric displacement rarely used?
increased time, infection
risk, equipment needs
Circumferential Measurements
Reliable
Can use software programs to convert to volume
Can measure limb every 3, 4, 8, or 12 cm
Include landmarks needed for garments
How can software programs be used to convert to volume?
Compare side-to-side
Compare changes over course of treatment
Compare over time
Pulses
Palpation
Doppler if needed
Other circulation methods to measure for lymphedema?
Capillary refill
Ankle-Brachial Index or Toe-Brachial Index on patients with lower extremity lymphedema
Screen patients with lower extremity lymphedema for DVT
Sensory Integrity
Perform monofilament testing on all patients with lymphedema
What can nerve entrapments be caused by?
tissue distention, edema, and inflammation
Patients at risk for neuropathy
Those with diabetes
Those who received chemotherapy
Stage 0
latent
No edema present
Reduced transport capacity of the lymphatic system
Most commonly due to surgery or radiation
Stage 1
Reversible
Edema that pits when digital pressure is applied
Greatly or completely reduces with elevation
No secondary skin changes
Stage 2
Spontaneously Irreversible
Does not pit when digital pressure is applied
Does not reduce substantially with elevation
Skin becomes fibrotic or brawny
May have frequent skin infections
Stage 3
Lymphostatic Elephantiasis
Extreme increase in limb volume
Deep skin folds and papillomas present
Frequent skin infections
Mild lymphedema
<3 cm interlimb difference
<20% limb volume increase