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Final HEME > lymphadenopathy > Flashcards

lymphadenopathy Flashcards

1
Q

lymphoid system comes from what embryologically?

A

mesenchymal yolk islands

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2
Q

the thymus stems from what embryonic structure?

A

foregut

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3
Q

what happens in the bursa equivalent?

A

B cell maturation

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4
Q

what are the 2 primary lyphoid organs?

A 
thymus
bursa equivalent (includes GALT)
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5
Q

the stroma of primary lymphoid organs: does it contain reticular fibers? what classification of tissue is it?

A

No reticular fibers
dense tissue (T cells)
no nodules

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6
Q

the stroma of secondary lymphoid organs: does it contain reticular fibers? what classification of tissue is it?

A

Yes reticular fibers

diffuse(T cells) and nodular (b cells)

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7
Q

what contains Hassal’s corpuscles?

A

thymus

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8
Q

what type of epithelium makes up the tonsils?

A

stratified squamous

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9
Q

what causes venous edema?

A

dec. protein

dec. osmolality

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10
Q

what causes lymphedema?

A

inc. protein and debris

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11
Q

what is seen in venous edema?

A

LE ulcers in gaitor distribution, above medial malleolus

hemosiderin build up

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12
Q

what is seen in lymphedema?

A

hyperkeratosis

stemmers sign- 2nd toe

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13
Q

genetic pattern of primary lymphedema?

A

AD

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14
Q

what is praecox lymphedema?

A

birth - 35 yo
F, puberty, left leg
most common

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15
Q

what test can you use for lymphedema?

A

stemmers sign

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16
Q

when do you see a reed sternberg cell?

A

hodgkin lymphoma

17
Q

what do you have an inc. risk of with HL?

A

herpes zoster

18
Q

histological findings of HL?

A

fish flesh appearance
nodular sclerosis
white pulp enlarged in spleen

19
Q

what happens to T cells in HL?

A

decreased

20
Q

what is immunologically seen in burkitts?

A

+ CD 19,20
+sIg
+CD10,34
c-myc 8:14 translocation

21
Q

what is immunologically seen in HL?

A
  • CD 19,20
    -sIg
    + CD 30, 15, 70
22
Q

when do you see a starry sky pattern histologically?

A

burkitts lymphoma

23
Q

what is the most common NHL?

A

B cell, diffuse

24
Q

with B cell diffuse NHL, what are you at inc. risk for?

A

HIV

25
Q

what chromosome translocation is seen with burkitts?

A

8:14

26
Q

in what lymphnodes do you see sarcoidosis?

A

lungs and mediastinal

27
Q

what infiltrates the lungs with sarcoid?

A

CD 4 T cells

28
Q

what is seen on xray with sardoid?

A

potato nodules

29
Q

what is seen histologically with sarcoid?

A

asteroid bodies

schaumann bodies

30
Q

what is sarcoid?

A

dz causing non caseating granulomas

31
Q

what is seen on labs with sarcoid?

A

inc. ACE

Inc. Vit D

32
Q

burkitts lymphoma is neoplastic proliferation of?

A

intermediate B cells, CD 20+

33
Q

burkitt lymphoma is associated with what virus?

A

EBV

Final HEME (6 decks)

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