LUPUS ERITEMATOSO SISTEMICO Flashcards

1
Q

GOLDS STANDAR DE NEFROPAIA LUPICCA

A

BIOPSIA RENAL

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2
Q

Indicación para realizar biopsia renal en un paciente con sospecha de nefropatía lúpica

A
  1. Proteinuria confirmada >0.5 en orina de 24 horas
    2 cociente proteína creatinina >0.5 en muestra matutina orina de 24 horas
  2. Deterioro inexplicado de la función renal
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3
Q

ANAS =

A

ANTICUERPOS ANTINUCLEARES

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4
Q

Manifestaciones neurológicas en LUPUS anticuerpos específicos

A

ANTI P-RIBOSOMAL

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5
Q

Anti-histona

A

Anticuerpos que aparecen en LUPUS x farmacos

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6
Q

Segundo anticuerpos más específico para LUPUS

A

Anti-DNA doble cadena

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7
Q

Anticuerpo más específico para el diagnóstico DE LUPUS

A

ANTI-SMITH

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8
Q

Fármacos se asocian a presentar lupus

A

HIDRALAZINA Y PROCAINAMIDA

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9
Q

Tx lupus

A
  1. Evitar exposición al sol (UV) mejor medida

*tx farmacologico
AINES : medidas generales
GLUCOCORTICOITES (piedra angular en recaídas) PREDNISONA
ANTIPALUDICOS a todos HIDROXICLOROQUINA : maculopatia
FARMES convencionales iniciar al momento x (METOTREXATO (ARTICULAR Y CUTÁNEA )
CICLOFOSFAMIDA (RENAL)AZATIOPRINA (PULMONAR Y HEMATOLOGICA)
FARMES BIOLÓGICOS
(Belimumab (BAAF) y rituximab ( anti.CD20) (cuando no funcionan los FARMES convencionales )

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10
Q

FARMES =

A

Ahorradores de esteroides

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11
Q

Temprana muerte (< 10 año)

A

Infecciones
Nefritis Lupita

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12
Q

Muerte tardía mayor 10 años

A

Cardiovasculares

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13
Q

Fármaco que no se puede utilizar embarazo

A

METOTREXATO

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14
Q

Porcentaje de riesgo de presentar una recaída en una paciente embarazada LUPUS

A

30%

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15
Q

Manifestaciones cutáneas anticuerpos específicos

A

ANTI LA

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