Lung Volumes, Pressures, Histology Flashcards

1
Q

haldane effect

A

hemoglobin becomes more acidic binding with oxygen

causes carbon dioxide and H+ protons to be expelled into the alveoli

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2
Q

bohr effect

A

at lung: hemoglobin binds 4 O2 and releases H+, Co2, DPG, and decreases temp

at tissues: hemoglobin releases O2 ,binds to H+, Co2, DPG, increases temp

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3
Q

normal breathing

500 ml

A

tidal volume

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4
Q

what controls tidal volume

A

pneumotaxic center

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5
Q

what limits inspirtation

A

stretch receptor fire when lung “full”

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6
Q

when lungs are full what is fired

A

herring breuer reflex

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7
Q

forced inspiration=

A

3000 ml

Inspiratory Reserve Volume

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8
Q

what does the inspiratory reserve volume shut off

A

herring breuer relfex

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9
Q

apneustic center in pons shuts off

A

pneumotaxic center

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10
Q

when pneumotaxic center is shut off this allows

A

deep breath, largest individual part of breathing

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11
Q

forced expiration

A

1100 ml

Expiratory reserve volume

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12
Q

what controls the expiratory reserve volume

A

rectus abdominus

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13
Q

keeps lungs from collapsing

A

residual volume

1200 ml

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14
Q

IRV+TV

A

inspiratory capacity

3500 ml

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15
Q

ERV + RV

A

functional residual capcity

2300 ml

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16
Q

IRV + TV +ERV

A

IC +ERV
4600 ml
vital capacity

17
Q

IRV + TV + ERV + RV

A

total lung volume

5800 ml

18
Q

air in pulmonary tree not involved with gas exchange

A

dead space

19
Q

what is an example of dead space

A

air in bronchi

20
Q

what is respiration controlled by

A

dorsal motor nucleus of vagus

21
Q

what controls the throat

A

nucleus ambiquous

CN 9,10,11

22
Q

what are the two main throat muscles

A

pharynx and larynx

swallowing and gag reflex

23
Q

pressure inside alveoli

slightly negative, allows for normal quiet inspiraiton

A

alveolar pressure

24
Q

air pressue opposes alveolar pressure

A

atmospheric pressure

25
Q

pressure of fluid in thin space between lung pleura and the chest wall pleura
negative pressure
keeps lungs open to their resting level

A

pleural pressure

26
Q

difference between alveolar pressure and pleural pressure

measures elastic forces in lung aka recoil pressure

A

transpulmonary pressure

27
Q

how far the lungs will expand per unit of increased transpulmonary pressure

A

compliance

28
Q

what is compliance dependent on

A

1-elastic forces

2-surface tension

29
Q

what does lack of surfactant at birth=

A

acute respiratory distress syndrome
aka
neonatal hyaline membrane disease

30
Q

what is the histology of the entire lung

A

Pseudo stratified ciliated columnar epithelium

PCCE

31
Q

what is the histology of the alveolar sacs

A

simple squamous epithelium

32
Q

type 1 pneumocytes

A

gas exchange

33
Q

type 2 pneumocytes

A

surfactant

decrease surface tension

34
Q

dust cells

A

macrophages

35
Q

fluid in the lungs collects in the

A

costodiaphragmatic recess

36
Q

trans pulmonic pressure

A

greatest at the bottom of inspiration

37
Q

water is how many more times absorbable than CO2

A

20x

38
Q

central chemoreceptors located in the brain stem primary and secondary to

A

primary sensitive to increase in CO2

secondary sensitive to decrease in O2

39
Q

peripheral chemoreceptors located in the carotid body and aortic body are primary and secondary to

A

primary to decrease O2

secondary to increase CO2