Lung Surfactant Flashcards

1
Q

Cells that produces surfactant

A

Type 2 Pneumocytes

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2
Q

MAIN component of surfactant

A

WATER

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3
Q

ACTIVE component of surfactant

A

DIPALMITOYL-PHOSPHATIDYLCHOLINE (DPPC)

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4
Q

Mechanism for DPPC reducing surface tension

A

Amphipathic nature (HYDROPHOBIC and HYDROPHILIC)

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5
Q

Effect of surfactant on Lung Compliance

A

INCREASE compliance

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6
Q

START of surfactant production

A

24TH WEEK AOG

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7
Q

MATURATION of surfactant

A

35TH WEEK AOG

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8
Q

DEFICIENCY in surfactant causes

A

NEONATAL RESPIRATORY DISTRESS SYNDROME (RDS)

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9
Q

Test for surfactant

A

Amniotic Lecithin:Sphingomyelin Ratio (Ratio of 2:1 or GREATER = MATURE fetal lungs)

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10
Q

Treatment for newborn RDS

A

STEROIDS
SURFACTANT

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