Lung Path Flashcards
PneumoThorax Define
Presence of Air in the pleural Cavitity
Accumulation of pressure-atelectasis
Clincal Features of a Pneumothorax
sudden onset or pain/tighenss
Increasing SOB
Pulmonary Embolism Define
occulsion of portion of pulomary vascular bed by an embolus
Risk Factors of Pulmonary Embolism
Venous Statis
Vessel Damage
Hypercoagulability
Clinical Features of Pulmonary Embolism
chest pain-Dyspnoea
Define Bronchogenic Carcinoma
malignant tumor arising from respiraoty tract epithelium
How does smoke as a carcinogen?
has Benzopyrene0induces tumor superessor gene TP53
Loss of function p53 include
reduced destruction of pre-maglinant cells
* accumulation of genetic mutations
* Proliferations of cancer cell
Process of Celluar change in Bronchogenic Carinoma
Metaplasia-Dysplasia-Carcinmona in situ- invasive carcinmoa
Upper Respiratory Tract
Common Cold
Viral Sore Throat
Influenza
Lower Respiratory Tract Infections
Influenza
Whooping Cough
Pneumonia
Tuberculosis
PathoPhysiology of Infections Rhiniits
- Cold invades nasal septum
- Acute inflammation of nasal mucosa
- Vasuclar permeabiltiy
- mucous secretion
*
PathoPhysilogy of Influenza
virus binds to respiratory epithelium
* flu virus attracts
* cells destroyed
*
Ssx of Influenza
- Fever
- Aches
- Mm Pain
- Joint Pain
- rapid onset
What is anitbiotic Resistance
Bacteria has become resistant
Clincal Features of a Whopping cough-last 6 weeks
- resembles common cold
- rapid consective coughs
- begins 4 weeks after onset
Pneumoia Define
inflammation of the lung
Clinical Signs of Consolidation
- Inspiratory Crackles
- Dullness to percussion
- Increased tactile fremitus
Define Allergic Asthma
Hypsensitivity Reaction
Excessive amounts of Immunoglobulin E
PathoPhysiology
- Intial Senstise
- Inflammatory
- Chemotic
Casue of Asthma
Airway Obstruction that results in inflammation-receptor hyperresponsivenss and mucus hypersecretion
Clincal Features of Asthma
SOB-Wheezing
Compenstory postures
Tachycardia
tachypnoea
Management of Asthma
- Prevents-Seretide
- Relievers-Bta adregnic agonists receptors
- muscurnic receptors antagonists
Chronic Bronchitis Define
cough least 3 weeks in at lesat 2 consective years
PathoPhysilogy of Chonic Bronchitis
mcus hyperscretion/persistent inflammation
Consequences of Chronic Bronchtis
Pulmonary Firbosos-recurre t infection-respiratyr faile
empyshema
permanet distension of air spaces distal to the treminal bronciloles
Patho-Physiology
Thinning of alveolar walls
Eventual Loss of alevor walls
Distension of remaing alveoi
Chronic Bronchitis-Blue Bloaters ahve what difference?
dont maintain their ventilatory drive
cyanotic
right heart failure-due to pulmonary hypertension
Epsynma-Pink Puffers have what diiferent
have respiratory drive
Barrel chest with mm wasting
What is Sleep Apnoea
reperated episodes of complete or parital obsructions of the pharynx during sleepp
risk factors of sleep apnoea
obesity
gender
smoking alchocol
thryoid conditons
Pahthophysiology of Sleep Apnoea
- Pharyngeal tiise is blocked-preventing venitlation
- reduce luman
- tonsils adenoids may be enlarged