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Y3 Respiratory > Lung cancer > Flashcards

Lung cancer Flashcards

1
Q

What are the different classifications of lung cancer?

A

Lung cancer is initially classified histologically as being either small cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC) due to the different features, management and prognosis see in the two groups.

  • SCLC accounts for around 15% of cases and generally carries a worse prognosis.
  • NSCLC can be broken down into (percentages refer to total lung cancer cases, not just NSCLC)
    • adenocarcinoma: c. 30%
      • alveolar cell carcinoma: not related to smoking, ++sputum
    • large cell: c. 10%
    • squamous: c. 35%
    • bronchial adenoma: mostly carcinoid
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2
Q

What is small cell lung cancer?

A

Small cell lung cancer (SCLC), previously referred to as oat cell carcinoma, is a malignant epithelial tumour arising from cells lining the lower respiratory tract.

It is an aggressive malignancy - 2/3 of pts have distant metastases at presentation.

Primarily develops in adult smokers

Histology:

  • tumour cells are small
  • densely packed
  • with scant cytoplasm
  • finely granular nuclear chromatin
  • absence of nucleoli
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3
Q

What is the aetiology of small cell lung cancer?

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4
Q

What are the risk factors for small cell lung cancer?

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5
Q

Summarise the epidemiology of small cell lung cancer

A
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6
Q

What are the presenting symptoms of small cell lung cancer?

A
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7
Q

What are the signs of small cell lung cancer O/E?

A
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8
Q

What are the primary investigations for ?small cell lung cancer?

A
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9
Q

What are some secondary investigations for ?small cell lung cancer?

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10
Q

What is squamous cell carcinoma?

A
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11
Q

What is the aetiology of squamous cell carcinoma?

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12
Q

What are the risk factors for squamous cell carcinoma?

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13
Q

Summarise the epidemiology of small cell lung cancer

A
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14
Q

What are the presenting symptoms of small cell lung cancer?

A
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15
Q

What are the signs of squamous cell carcinoma O/E?

A
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16
Q

What are the primary investigations for ?squamous cell carcinoma?

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17
Q

What are some secondary investigations for ?squamous cell carcinoma?

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18
Q

What is large cell carcinoma?

A
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19
Q

What is the aetiology of large cell carcinoma?

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20
Q

What are the risk factors for large cell carcinoma?

A
21
Q

Summarise the epidemiology of large cell carcinoma

A
22
Q

What are the presenting symptoms of small cell lung cancer?

A
23
Q

What are the signs of large cell carcinoma O/E?

A
24
Q

What are the primary investigations for ?large cell carcinoma?

A
25
Q

What are some secondary investigations for ?large cell carcinoma?

A
26
Q

What is adenosquamous carcinoma?

A
27
Q

What is the aetiology of adenosquamous carcinoma?

A
28
Q

What are the risk factors for adenosquamous carcinoma?

A
29
Q

Summarise the epidemiology of adenosquamous carcinoma

A
30
Q

What are the presenting symptoms of adenosquamous carcinoma?

A
31
Q

What are the signs of adenosquamous carcinoma? O/E?

A
32
Q

What are the primary investigations for ?adenosquamous carcinoma?

A
33
Q

What are some secondary investigations for ?adenosquamous carcinoma?

A
34
Q

What is small cell lung cancer?

A
35
Q

What is the aetiology of small cell lung cancer?

A
36
Q

What are the risk factors for small cell lung cancer?

A
37
Q

Summarise the epidemiology of small cell lung cancer

A
38
Q

What are the presenting symptoms of small cell lung cancer?

A
39
Q

What are the signs of small cell lung cancer O/E?

A
40
Q

What are the primary investigations for ?small cell lung cancer?

A
41
Q

What are some secondary investigations for ?small cell lung cancer?

A
42
Q

What is bronchial adenoma?

A
43
Q

What is the aetiology of bronchial adenoma?

A
44
Q

What are the risk factors for bronchial adenoma?

A
45
Q

Summarise the epidemiology of bronchial adenoma

A
46
Q

What are the presenting symptoms of bronchial adenoma?

A
47
Q

What are the signs of bronchial adenoma O/E?

A
48
Q

What are the primary investigations for ?bronchial adenoma?

A
49
Q

What are some secondary investigations for ?bronchial adenoma?

A

Y3 Respiratory (21 decks)

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