LT2 Flashcards
What is not a definition of cellular respiration?
A. Provides less energy (ATP) from glucose than glycolysis
B. Also known as aerobic respiration/pathway and oxidative phosphorylation
C. Process in which cells consume oxygen and produce carbon dioxide
D. Captures energy stored in lipids and amino acids
A. more*
Match the stages of cellular respiration:
Stage 1 A. Oxidation of acetylCoA
Stage 2 B. Production of acetylCoA
Stage 3 C. Oxidative phosphorylation
Stage 1-B, 2-A, 3-C
Match the corresponding pathways and their compartments:
A. Glycolysis a. Mitochondrial matrix
B. Oxidative phosphorylation b. Cytosol
C. Citric acid cycle/ TCA / Krebs cycle c. inner membrane of the mitochondria
A-b, B-c, C-a
All are features of Pyruvate Oxidation, except:
A. Irreversible reactions
B. Involves oxidative decarboxylation (removal of carboxyl group)
C. AcetylCoA is an energy rich compound because of the presence of a thioester
D. Reversible reactions
D
1 pyruvate is equivalent to 1 acetylCoA in pyruvate oxidation.
True or False
True
Pyruvate dehydrogenase (PDH) complex is a multienzyme complex. Which is responsible for the conversion to Acetyl, has a lipoamide, and coenzyme A?
A. Pyruvate dehydrogenase (E1)
B. Dihydrolipoamide transacetylase (E2)
C. Dihydrolipoamide dehydrogenase (E3)
B
Pyruvate dehydrogenase (PDH) complex is a multienzyme complex. Which is responsible for the regeneration of subunits, has a FAD, and NAD+?
A. Pyruvate dehydrogenase (E1)
B. Dihydrolipoamide transacetylase (E2)
C. Dihydrolipoamide dehydrogenase (E3)
C
Pyruvate dehydrogenase (PDH) complex is a multienzyme complex. Which is responsible for decarboxylating pyruvate, and has TPP as prosthetic group?
A. Pyruvate dehydrogenase (E1)
B. Dihydrolipoamide transacetylase (E2)
C. Dihydrolipoamide dehydrogenase (E3)
A
If the cell has high amount of NAD+ will the activity of the PDH complex increase or decrease?
- it will increase because NAD+ helps perform the reaction & NADH is a product of the reaction.
For every 2 molecules of glucose entering the aerobic pathway, how many acetylCoA molecules will be produced?
- 4 because 1 glucose molecule makes 2 pyruvate and each pyruvate is equivalent to 1 acetylCoA
Why should citrate be isomerized to isocitrate in step 2 of the TCA cycle?
- The alcohol in citrate is tertiary while the alcohol in isocitrate is secondary. Tertiary alcohols cannot perform reactions. If there’s no isomerization, we won’t be able to oxidize and proceed to the next step which is the oxidation of the alcohol if it is tertiary.
One round of the TCA cycle produces the following per 1 acetylCoA:
____ CO2 ; ____ NADH ; ____ FADH2 ; ____ GTP
- 2 CO2 (from steps 3 and 4); 3 NADH (steps 3,4, and 8); 1 FADH2 (from step 6); 1 GTP (from step 5)
