Lt : Therapy Of Erectile Dysfunction Flashcards
Non-specific phosphodiesterase inhibitor that increases CAMP and CGAMP levels in penile erectile
Papaverine
Is a drug used in treatment of ED known as smooth muscle relaxant and vasodilator
Papverine
Is a drug highly effective in men with psychogenic and neurogenic erectile dysfunction and administered IV
Papverine
What hormones are used as hormone replacement therapy in treatment of erectile dysfunction?
- Testosterone
- Methyltestosterone
- Testosterone cypionate
What are indicated in the treatment of erectile dysfunction stemming from hypogonadism?
Hormone replacement therapy:
Testosterone
Methyltestosterone
Testosterone cypionate
Is a hormone replacement therapy to treat ED that is given orally?
Methyltestosterone
Is a hormone replacement therapy that is used to treat ED and given transdermally?
Testosterone
Is a hormone replacement therapy used to treat ED and given intramuscularlu
Testosterone cypionate
What is the difference between transdermal delivery and intramuscular in HRT to treat ED?
Transdermal delivery system can provide more constant serum testosterone level than intramuscular injections, but they are more expensive
Is a PGE1 analog with vasodilation properties
Alprostidil
Is a drug used to treat ED by activating PGE1 receptors resulting in generation of CAMP and relaxation of corpus cavernous smooth muscle
Alprostidil
How we administer Alprostidil?
It can be administered by injection directly into the corpus cavernous smooth muscle
Or transurethral suppository in the treatment of erectile dysfunction
What are adverse effects of Alprostidil?
Cardiac arrhythmias
Hypotension
Heart failure
Can cause prolonged erection (priapism) in some people
What is a drug that treats ED and causes prolonged erection (priapism) in some patients
Alprostidil
What is a non-selective alpha adrenoreceptor blocking agent
Phentolamine
How we administer phentolamine?
It has been used orally and intracavernously in the treatment of erectile dysfunction
It is administered by intracavernous injection
What is a more selective alpha 1 adrenorecptor antagonist ?
Tamsulosin
What is contraindicated in patients taking nitrates or alpha 1 Adrenergic antagonist?
Sildenafil
Is a selective inhibitor of PDE-5 in the corpus cavernosum?
Sildenafil (viagra)
It was originally developed as treatment for hypertension but it is effective in treating erectile dysfunction
Sildenafil (viagra)
What is another name for sildenafil?
Viagra
What is the benefit of the selective inhibitor of PDE-5 in corpus cavernosum?
The selective inhibition of PDE-5 potentials the vasodialating effects of nitric oxide
What are drugs that have similar actions as sidlinifin and are taken shortly before intercourse?
Tadalafil (cialis)
Vardenafil (levitra)
What is a drug that has similar action to sidlinfin and is taken on daily basis?
Cialis
The interaction between which drug and nitrates and alpha Adrenergic antagonist lead to severe drop in pressure?
Sidlinfil
What is alpha 1 Adrenergic antagonist that can interact with sudnifil?
Prazosin
Is a condition characterized by inability to achieve and maintain erectile dysfunction for a satisfactory sexual intercourse?
Erectile dysfunction
Which age group gets erectile dysfunction?
ED can occur in as high as 50% of men aged 40 years and over and the percentage increases with age
