Lt : Therapy Of Erectile Dysfunction Flashcards

1
Q

Non-specific phosphodiesterase inhibitor that increases CAMP and CGAMP levels in penile erectile

A

Papaverine

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2
Q

Is a drug used in treatment of ED known as smooth muscle relaxant and vasodilator

A

Papverine

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3
Q

Is a drug highly effective in men with psychogenic and neurogenic erectile dysfunction and administered IV

A

Papverine

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4
Q

What hormones are used as hormone replacement therapy in treatment of erectile dysfunction?

A
  1. Testosterone
  2. Methyltestosterone
  3. Testosterone cypionate
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5
Q

What are indicated in the treatment of erectile dysfunction stemming from hypogonadism?

A

Hormone replacement therapy:
Testosterone
Methyltestosterone
Testosterone cypionate

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6
Q

Is a hormone replacement therapy to treat ED that is given orally?

A

Methyltestosterone

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7
Q

Is a hormone replacement therapy that is used to treat ED and given transdermally?

A

Testosterone

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8
Q

Is a hormone replacement therapy used to treat ED and given intramuscularlu

A

Testosterone cypionate

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9
Q

What is the difference between transdermal delivery and intramuscular in HRT to treat ED?

A

Transdermal delivery system can provide more constant serum testosterone level than intramuscular injections, but they are more expensive

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10
Q

Is a PGE1 analog with vasodilation properties

A

Alprostidil

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11
Q

Is a drug used to treat ED by activating PGE1 receptors resulting in generation of CAMP and relaxation of corpus cavernous smooth muscle

A

Alprostidil

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12
Q

How we administer Alprostidil?

A

It can be administered by injection directly into the corpus cavernous smooth muscle
Or transurethral suppository in the treatment of erectile dysfunction

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13
Q

What are adverse effects of Alprostidil?

A

Cardiac arrhythmias
Hypotension
Heart failure
Can cause prolonged erection (priapism) in some people

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14
Q

What is a drug that treats ED and causes prolonged erection (priapism) in some patients

A

Alprostidil

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15
Q

What is a non-selective alpha adrenoreceptor blocking agent

A

Phentolamine

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16
Q

How we administer phentolamine?

A

It has been used orally and intracavernously in the treatment of erectile dysfunction
It is administered by intracavernous injection

17
Q

What is a more selective alpha 1 adrenorecptor antagonist ?

A

Tamsulosin

18
Q

What is contraindicated in patients taking nitrates or alpha 1 Adrenergic antagonist?

A

Sildenafil

19
Q

Is a selective inhibitor of PDE-5 in the corpus cavernosum?

A

Sildenafil (viagra)

20
Q

It was originally developed as treatment for hypertension but it is effective in treating erectile dysfunction

A

Sildenafil (viagra)

21
Q

What is another name for sildenafil?

A

Viagra

22
Q

What is the benefit of the selective inhibitor of PDE-5 in corpus cavernosum?

A

The selective inhibition of PDE-5 potentials the vasodialating effects of nitric oxide

23
Q

What are drugs that have similar actions as sidlinifin and are taken shortly before intercourse?

A

Tadalafil (cialis)

Vardenafil (levitra)

24
Q

What is a drug that has similar action to sidlinfin and is taken on daily basis?

A

Cialis

25
Q

The interaction between which drug and nitrates and alpha Adrenergic antagonist lead to severe drop in pressure?

A

Sidlinfil

26
Q

What is alpha 1 Adrenergic antagonist that can interact with sudnifil?

A

Prazosin

27
Q

Is a condition characterized by inability to achieve and maintain erectile dysfunction for a satisfactory sexual intercourse?

A

Erectile dysfunction

28
Q

Which age group gets erectile dysfunction?

A

ED can occur in as high as 50% of men aged 40 years and over and the percentage increases with age