LPS ERTHMTSS

Question 1

→ collection of autoimmune diseases

Answer 1

LUPUS ERYTHEMATOSUS

Question 2

• “wolf”

Answer 2

LUPUS

Question 3

“reddened”

Answer 3

ERYTHEMATOSUS

Question 4

What are the classifications of LUPUS ERYTHEMATOSUS?

Answer 4

● Discoid Lupus Erythematosus
● Systemic Lupus Erythematosus (SLE)
● Drug-induced Lupus Erythematosus
● Neonatal Lupus Erythematosus

Question 5

CLASSIFICATION OF LE

-is an autoimmune disease
-the immune system of the body mistakenly attacks healthy tissue
-it can affect the skin, joints, kidneys, brain, and other organs

Answer 5

SYSTEMIC LUPUS ERYTHEMATOSUS

Question 6

production of antibodies against the tissues of your own

Answer 6

AUTOIMMUNITY

Question 7

What are the Effects of AUTOIMMUNE DISORDER?

Answer 7

✓ Failure to display self-antigens
✓ Presence of genetic abnormalities
✓ Self-reactive clones of T-cells & B-cells

Question 8

CLASSIFICATION OF LE:

• is a chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp and at times on other body areas.
  -These lesions develop as a red, inflamed patch with a
  scaling and crusty appearance. The center areas may appear lighter in color with a rim darker than the normal skin.

Answer 8

DISCOID LUPUS ERYTHEMATOSUS (DLE)

Question 9

CLASSIFICATION OF LE:

What are the 3 DIVISIONS OF DLE?

Answer 9

-LOCALIZED
-GENERALIZED
-CHILDHOOD DISCOID LUPUS ERYTHEMATOSUS

Question 10

CLASSIFICATION OF LE:

● non contagious, chronic, progressive inflammatory
disease of the connective tissue
● cause is UNKNOWN
● Chronic, progressive inflammatory connective tissue
disorder that can cause major body and system failure
● Characterized by spontaneous remission (the state
of absence of disease activity in patients with a
chronic illness, with the possibility of return of disease)

Answer 10

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Question 11

CLASSIFICATION OF LE:

What is the cause of SLE?

Answer 11

UNKNOWN

Question 12

ACR DIAGNOSTIC CRITERIA

Answer 12

SKIN CRITERIA
-Butterfly rash
-Discoid rash
-Photosensitivity
-Oral ulcers

SYSTEMIC CRITERIA
-Arthritis
-Serositis
-Kidney disorder
-Neurologic disorder

LABORATORY CRITERIA
-Hematologic abnormalities
-Immunologic disorder
-Antinuclear disorder

Question 13

ACR
SLE CLASSIFICATION CRITERIA

Answer 13

1. Serositis
2. Oral ulcers
3. Arthritis
4. Photosensitivity
5. Blood/Hematologic disorder
   a. hemolytic anemia
   b. leukopenia of <4.0 x10^9
   c. lymphopenia of <1.5 x 10^9
   d. thrombocytopenia <100 x 10^9
6. Renal disorder
   a. Proteinuria >0.5gm/24hot 3+ dipstick
   b. cellular casts
7. Antinuclear antibody (+ANA)
8. Immunologic disorders
9. Neurological disorder
   a. seizures
   b.psychosis

Question 14

MEDICAL MANAGEMENT OF LE

Answer 14

1. Maintenance of skin integrity
2. Healthy lifestyle and stress reduction
3. Proper nutrition
4. Promotion of comfort
5. Increase client’s independence
6. Maintain emotional being

Question 15

MEDICATIONS OF LE

Answer 15

• ANTI-INFLAMMATORY ANALGESICS
  -ANTIMALARIAL DRUG
  -CORTICOSTEROIDS
  -TOPICAL COSTICOSTEROIDS
  -CYTOTOXIC AGENTS OR ANTINEOPLASTIC