Lower respiratory tract infections Flashcards

1
Q

Should the lower airway be colonised with bacteria?

A

No

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2
Q

What is acute bronchitis?

A

Inflammation of the bronchi usually caused by infection

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3
Q

What pathogens usually cause acute bronchitis?

A

Viruses usually

Bacteria:
H. influenzae
Strep. pneumonia
Many more

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4
Q

What are the symptoms of acute bronchitis?

A

Cough: productive or non
SOB
Wheeze
Fever

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5
Q

Do you get systemic involvement in bronchitis?

A

No, but you do get a fever

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6
Q

What would you find on a CXR with acute bronchitis?

A

Not a lot

No focal consolidation like there would be with pneumonia

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7
Q

Investigations for acute bronchitis.

A

ABG: if O2 levels are low and CO2 levels high then consider admission

CXR: no consolidations signs of pneumonia

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8
Q

Treatment of acute bronchitis.

A

If viral, just supportive care: pain relief, fluids, rest.

If bacterial: antibiotics

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9
Q

What problems can occur if you have COPD or asthma and you get acute bronchitis?

How would you manage this?

A

Exacerbation

Manage with inhalers + steroids

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10
Q

What is augmentin?

A

An antibiotic containing amoxicillin and clavulanate

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11
Q

What is pneumonia?

A

Inflammation of lung parenchyma

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12
Q

Who is at risk of getting pneumonia?

A

Extremes of age

COPD and other chronic lung diseases

Immunocompromised

Nursing home residents

Impaired swallowing

Diabetes

Congestive heart failure

Alcoholics + drug users

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13
Q

How is pneumonia classified?

A

Anatomically:

  • lobar
  • bronchopneumonia

Aetiologically: by the pathogen causing it

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14
Q

What are the causes of pneumonia?

A

Infection:

  • usually bacteria
  • sometimes virus

Unknown

Chemical
- aspiration of vomit

Radiotherapy

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15
Q

Which pathogens most commonly cause pneumonia?

A

Bacteria

  • S. pneumonia
  • Mycoplasma species
  • Chlamydophila pneumonia
  • Legionella
  • H. influenzae
  • Mycobacterium tuberculosis
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16
Q

Where do people come across Legionella?

A

Water tanks
Stagnant water
Travel

17
Q

What is consolidation?

A

Alveolar space that contains liquid instead of gas

It appears as white on an X-ray
It is a sign of pneumonia

18
Q

How does consolidation occur?

A

When an infection occurs in the distal airways, an inflammatory response occurs

So neutrophils and inflammatory exudate fill the alveolar space

Fluid accumulates = consolidation

19
Q

What are symptoms of pneumonia?

A
Fever
Cough
Sputum sometimes
SOB
Pleuritic chest pain
Systemic features: fever, night sweats
Extra-pulmonary features: neurological
20
Q

What can sputum tell you about pneumonia?

A

Rusty sputum is suggestive of S. pneumonia

Non-productive suggests Mycoplasma, Chlamydophila, Legionella

21
Q

What are the signs of pneumonia?

A

Abnormal vital signs:

  • fever
  • raised HR
  • raised resp rate
  • low BP

Signs of lung consolidation on percussion and auscultation

Hypoxia, signs of respiratory failure

22
Q

What are the signs of lung consolidation you can hear?

A
Dull to percussion
Decreased air entry
Bronchial breath sounds
Crackles plus wheeze
Aegophony
23
Q

What is aegophony and how do you test for it?

A

Ask the patient to say ‘e’ and listen to the lungs with a stethoscope

If they show aegophony the ‘e’ sound they are making will sound like an ‘a’

24
Q

Investigations for pneumonia?

A

CXR: show areas of consolidation
Also look for cavities (TB) and signs of cancer

Sputum

Bloods:

  • WBCs - marker for severity
  • U&E
  • LFT
  • CRP - marker for severity

Pulse oximetry

ABG: low O2 and high CO2 means it is severe

Microbiological tests

Urinalysis

25
On an X-ray what would multi-lobar consolidation suggest the pathogen is?
S. pneumonia S. aureus Legionella
26
On an X-ray what would multiple abscesses or pneumoatoceles suggest the pathogen is?
S. aureus
27
What are pneumatoceles?
Cavities filled with air
28
On an X-ray what would an upper lobe cavity suggest the pathogen is?
Klebsiella pneumoniae
29
Management of pneumonia?
Antimicrobials depending on the pathogen Analgesia Oxygen if hypoxic Admit to ITU/HDU if necessary
30
What is CAP?
Community acquired pneumonia
31
Which micro-organisms are usually responsible for hospital acquired pneumonias?
Gram negative bacilli | Staph. aureus
32
What is a CURB-65 score?
C - Confusion: use the abbreviated mental test (score ≤8) U - Urea >7mmol/L R - Respiratory rate ≥30/min B - Blood Pressure 65 years 1 point for each A score ≥3 is severe pneumonia ≥2 requires hospitalisation
33
What's the difference between an empyema and an abscess?
Empyema: a collection of pus in an already existing cavity Abscess: collection of pus in a newly formed cavity
34
What is a pleural empyema?
Collection of pus in the pleural cavity
35
What causes pleural empyema?
When bacteria invade the pleural space
36
What are the clinical features of pleural empyema?
Fever + inflammation markers that don't settle with antibiotics Pain on deep inspiration Signs of pleural collection: stony dull to percussion, reduced air entry
37
What is the treatment for pleural empyema? | Why do you have to be quick?
Drain the pus If it is left for too long it will become gelatinous, and will have to be removed surgically
38
How can you prevent pneumonia?
Polysaccharide pneumococcal vaccination Influenza vaccine Smoking cessation
39
Who is the Polysaccharide pneumococcal vaccination offered to?
Those over age 65 Splenic dysfunction Immunocompromised Chronic medical conditions