Lower Respiratory Drugs Flashcards
Class action for Albuterol and Salmeterol
Beta 2 Adrenergic Agonist
Albuterol… LABA or SABA?
SABA
Salmeterol… LABA or SABA
LABA
Albuterol Route
inhaler/nebulizer (5-15 min onset)
Salmeterol Route
inhaler
Rescue inhalor
Albuterol
Maintenance Inhalers
Salmeterol, Ipratropium, Fluticasone
Albuterol trade name
Pro Air
Salmeterol trade name
Severent Diskus
Albuterol indications
acute bronchospasm: Asthma Attack, COPD Exacerbation, pneumonia
prevention of exercise induced asthma
Salmeterol indications
prevention of Asthma Attack, COPD Exacerbation, and exercise induced asthma
Albuterol and Salmeterol MoA
Beta 2 selective adrenergic agonists- BRONCHODILATION
Contraindications of Albuterol and Salmeterol
conditions exacerbated by sympomimetic effects
drug drug interactions with beta adrenergic antagonists
AE/SE of Albuterol and Salmeterol
sympomimetic stimulation: cardiac arrhythmias, tachycardia, HTN, sweating, tremors, worsened bronchospasm
Black Box Warning with Salmeterol
asthma related deaths… use corticosteroid to decrease risk
Nursing implications with Albuterol
use to treat symptoms or as scheduled… overuse can cause AE/SE. administer 30-60 min before exercise
Nursing implications with Salmeterol
use on schedule
Class action for ipratropium
respiratory cholinergic antagonist
Trade name for ipratropium
Atrovent
Route for Ipratropium
inhaler
Indications for ipratropium
prevention of bronchospasm
MoA for ipratropium
blocks acetylcholine BRONCHODILATION
AE/SE for ipratropium
dry mouth, nasal congestion, heart palpitations, other sympathetic effects are rare
Nursing implications for ipratropium
not a rescue inhalor
Class action for Fluticasone
inhaled corticosteroid
Route for fluticasone
inhaler
Trade name for fluticasone
Flovent
Indications for fluticasone
prevention and treatment of asthma
MoA for fluticasone
decrease inflammatory response in airways
AE/SE for fluticasone
sore throat, hoarseness, coughing, dry mouth, pharyngeal and laryngeal infections (oral thrush), rare systemic reaction
Nursing implications for fluticasone
assess mucous membranes- fungal infections not a rescue inhaler
Patient Education for Fluticasone
rinse mouth after each inhalation
Class action for Montelukast
leukotriene
Route for Montelukast
oral
Trade name for montelukast
Singulair
Indication for montelukast
prophylaxis in adults and children
MoA of montelukast
selectively blocks Leukotriene production receptors
reduces inflammation
AE/SE for montelukast
headache, nausea, diarrhea
Nursing Implications for montelukast
not a rescue medication
can be used for children 1yo and older
Class action for Theophylline and Aminophylline
Xanthine Derivatives
Route for theophylline
oral
route for aminothylline
IV
Indications for theophylline
prevention of bronchospasm
Indications for aminophylline
reversal of bronchospasm
MoA of theophylline and aminophylline
direct effect on smooth muscles on respiratory tract- bronchi and blood vessels
metabolized to caffeine
Contraindications for theophylline and aminophylline
cardiac disease
AE/SE for Aminophylline and theophylline
related to blood vessels: GI Upset, nausea, irritability, tachycardia to seizure, brain damage, death
Nursing implications for theophylline and aminphylline
narrow therapeutic window, monitor levels for drug toxicity, smoking increases metabolism (decrease levels)