Loop of Henle Flashcards
what does the liver do to lipid soluble drugs and pollutants to facilitate their excretion
makes them polar (water soluble)
guess this makes it easier for them to be secreted and excreted from osmotic pressures etc
fluid in proximal tubule is iso/hypo/hyper osmotic to plasma
isosmotic
what is the osmolarity of plasma
300mOsmoles/L
how are do proximal tubule and plasma have the same osmolarity
because all movements have been accompanied by H20 movements
where are the proximal and distal tubules, cortex or medulla
cortex
what does the loop of henle do
concentrates urine
what is the minimum concentration of urine that can be produced
30-50mOsmoles/L (10 times weaker than plasma)
which loops of henle establish a hypertonic medullary gradient
ones in the medulla. i.e. belonging to juxtamedullary nephrons
which limb of henle loop is impermeable to H2O
ascending limb
permeabilities of descending limb
H2O permeable
NaCl impermeable
which limb of henle loop is impermeable to NaCl
descending limb
which limb of henle loop is permeable to NaCl
ascending limb
effect of ascending limb on concentration
reduces concentration (pumps out NaCl)
which limb of henle dilutes the fluid
ascending
which limb of henle concentrates the fluid
descending